Pyrene phosphoramidite dU

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Pyrene phosphoramidite dU

Pyrene phosphoramidite dU

Pyrene phosphoramidite dU
Catalog Number Size Price Quantity
R10-0010 -- $--

Pyrene is polycyclic aromatic hydrocarbon which is well-known for its ability to intercalate into DNA. Pyrene features intense blue fluorescence. Its parameters depend strongly on fluorophore microenvironment. Therefore, fluorescence spectra of pyrene are used for the extraction of structural information about site surrounding pyrene. Two pyrenes in close proximity usually form excimers easily detectable by excimer fluorescence. Pyrene can also be a FRET donor to other fluorophores such as perylene.With this phosphoramidite, pyrene can be introduced into DNA by means of automated synthesis. This pyrene phosphoramidite contains hydrocarbon moiety rigidly attached to deoxyuridine. This reagent allows to attach pyrene fragment to 5', internal, or 3' position (using universal support).

Chemical Information
Catelog Number: R10-0010
Product Name: Pyrene phosphoramidite dU
Molecular Formula: C57H55N4O8P
Molecular Weight: 955.04
Purity: NMR 1H (95%), 31P, HPLC-MS
Solubility: good in dichloromethane and acetonitrile
CAS Number: 199920-17-7
Product Specification
Appearance: yellowish foam
ε, L⋅mol-1⋅cm-1: 12600; 21900; 16000; 14200
Fluorescence quantum Yield: ~0.1
Storage Conditions: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 2 weeks. Avoid prolonged exposure to light. Desiccate.
Excitation Maximum (nm): 260; 282; 365; 392
Emission Maximum (nm): 460

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