BBQ-650 Pro Phosphoramidite

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BBQ-650 Pro Phosphoramidite

BBQ-650 Pro Phosphoramidite

Catalog Number R10-0035
Category Other Quencher
Molecular Formula C71H87N10O12P
Molecular Weight 1303.51
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Product Introduction

BBQ-650 Pro Phosphoramidite is a fluorescent labeling reagent used in oligonucleotide synthesis. It contains a BlackBerry Quencher 650 (BBQ-650) fluorophore attached to a hydroxyprolinol-based phosphoramidite moiety. BlackBerry Quencher (BBQ-650) exhibits a broad absorption profile from 550nm to 750nm, centered at 650nm. The hydroxyprolinol linker provides a rigid, non-nucleosidic scaffold for efficient incorporation of the BBQ-650 label at the 5' end of DNA or RNA sequences during automated solid-phase synthesis. It is commonly used in multiplex PCR, DNA sequencing, and fragment analysis applications.

  • Chemical Information

Chemical Information

Synonyms BBQ-650 Phosphoramidite (hydroxyprolinol); (3R,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-1-(6-(4-((9-((2,5-dimethoxy-4-((4-nitrophenyl)diazenyl)phenyl)diazenyl)-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-yl)oxy)butanamido)hexanoyl)pyrrolidin-3-yl (2-cyanoethyl) diisopropylphosphoramidite
SMILES COC1=CC=C(C(C2=CC=CC=C2)(OC[C@@H]3C[C@H](CN3C(CCCCCNC(CCCOC4=C(N=NC5=CC(OC)=C(N=NC6=CC=C([N+]([O-])=O)C=C6)C=C5OC)C=C7CCCN8CCCC4=C87)=O)=O)OP(OCCC#N)N(C(C)C)C(C)C)C(C=C9)=CC=C9OC)C=C1
InChI InChI=1S/C71H87N10O12P/c1-49(2)80(50(3)4)94(92-42-18-37-72)93-60-44-57(48-91-71(52-20-11-9-12-21-52,53-25-33-58(86-5)34-26-53)54-27-35-59(87-6)36-28-54)79(47-60)68(83)24-13-10-14-38-73-67(82)23-17-41-90-70-61-22-16-40-78-39-15-19-51(69(61)78)43-64(70)77-76-63-46-65(88-7)62(45-66(63)89-8)75-74-55-29-31-56(32-30-55)81(84)85/h9,11-12,20-21,25-36,43,45-46,49-50,57,60H,10,13-19,22-24,38-42,44,47-48H2,1-8H3,(H,73,82)/t57-,60+,94?/m0/s1
InChIKey WPSKKSDYOJEVMW-YEPVNGELSA-N

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