Eclipse^® Quencher Phosphoramidite | 916753-64-5

Product Introduction

Eclipse® Quencher Phosphoramidite is a paramount constituent employed in the fabrication of oligonucleotides, emerges as a pivotal ensemble. Its functions lie in its ability to dampen the fluorescence signal within nucleotide probes, consequently facilitating meticulous identification of distinctive DNA or RNA sequences. It substantiates its worth by contributing to the proficiency of diagnostic assays and molecular biology research, consequently augmenting the detection and scrutiny of assorted maladies and genetic irregularities.

Chemical Information
Synonyms	EclipseQ Phosphoramidite; Eclipse Quencher Phosphoramidite; 4-N-methyl-N-(4'-nitro-2'-chloroazobenzen-4-yl)-aminobutanamido-1-(2-O-dimethoxytrityloxymethyl)-pyrrolidin-4-yl-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramdite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[4-[[4-[2-(2-chloro-4-nitrophenyl)diazenyl]phenyl]methylamino]-1-oxobutyl]-3-pyrrolidinyl 2-cyanoethyl ester, rel-; rel-(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[4-[[4-[2-(2-chloro-4-nitrophenyl)diazenyl]phenyl]methylamino]-1-oxobutyl]-3-pyrrolidinyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; 5'-Eclipse Amidite
IUPAC Name	rel-(3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-1-(4-((4-((2-chloro-4-nitrophenyl)diazenyl)phenyl)(methyl)amino)butanoyl)pyrrolidin-3-yl (2-cyanoethyl) diisopropylphosphoramidite
Canonical SMILES	N#CCCOP(OC1CN(C(=O)CCCN(C2=CC=C(N=NC3=CC=C(C=C3Cl)N(=O)=O)C=C2)C)C(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C1)N(C(C)C)C(C)C
InChI	InChI=1/C52H61ClN7O8P/c1-37(2)59(38(3)4)69(67-32-12-30-54)68-48-33-45(36-66-52(39-13-9-8-10-14-39,40-16-25-46(64-6)26-17-40)41-18-27-47(65-7)28-19-41)58(35-48)51(61)15-11-31-57(5)43-22-20-42(21-23-43)55-56-50-29-24-44(60(62)63)34-49(50)53/h8-10,13-14,16-29,34,37-38,45,48H,11-12,15,31-33,35-36H2,1-7H3/t45-,48+,69?/s2
InChI Key	CXNVOZCFZYENEQ-SOWLJRCBNA-N
Appearance	Black solid
Boiling Point	962.2±65.0 °C (Predicted)