Applications
Fluorescent Dyes for Peptide Labeling
2024-11-15
Fluorescent markers are widely used in protein function research and drug screening. Fluorescently labeled peptides are often used to detect the activity of target proteins. The high-throughput activity screening methods developed from this are applied to drug screening and drug development of disease-related target proteins (such as various kinases, phosphatases, and peptidases). Therefore, fluorescent modification of peptides is an important aspect in the field of peptide synthesis.
Fluorescent Dyes for Antibody Labeling
2024-11-04
Fluorescent antibody labeling technology uses chemical methods to covalently couple fluorescent dyes to specific antibodies. After the antibody-fluorescent complex specifically binds to the corresponding antigen, the fluorescent signal is observed through instruments such as fluorescence microscopes to achieve the positioning, qualitative or quantitative detection of the target sample. It provides researchers with an effective method to study molecular and cellular structures in biological systems.
Fluorescent Dyes for Protein Labeling
2024-09-04
Fluorescent dyes are a class of chemicals that can emit fluorescence when excited by light of a specific wavelength. They have high sensitivity, high selectivity, and good photostability, and are widely used in various analytical techniques in biomedicine and biological research. There are many types of fluorescent dyes, including organic small molecule dyes, fluorescent proteins, and quantum dots, each with different spectral characteristics and applicable ranges. In terms of protein labeling, fluorescent dyes bind to target proteins through covalent or non-covalent bonds, and the localization and dynamic changes of proteins can be visually observed under a microscope. This technology is widely used in cell biology, molecular biology, and drug development.
Cyanine Dyes for RNA Labeling
2024-08-13
Cyanine is a class of organic dyes with unique optical properties, which are widely used in biomedicine and biotechnology. Its fundamental structure is a polyene chain made up of two aromatic rings joined by a conjugated double bond chain. Particularly popular for use in RNA labeling are cyanine dyes. Researchers can track and quantify RNA molecules quantitatively by using cyanine dyes to link them to RNA molecules by chemical coupling or covalent bonding technologies. The study of RNA distribution, dynamic changes, and interactions has benefited immensely from this technique.
Cyanine Dyes for DNA Labeling
2024-08-10
Cyanine dyes are a class of organic dyes with extremely high fluorescence sensitivity and diverse bonding capabilities, and are widely used for DNA labeling in biological and medical research. Since cyanine dyes have special optical and chemical characteristics that make them a valuable tool for molecular biology and genetics research, they are used in the DNA labeling process. For example, cyanine dyes offer a high temporal and spatial resolution method for examining the dynamics of DNA molecules in single-molecule FRET (Förster resonance energy transfer) investigations.
Cyanine Dyes for Nucleotide Labeling
2024-07-15
Cyanine dyes are a class of fluorescent dyes widely used in the fields of biomedicine and biotechnology. They can efficiently limit the interference of background fluorescence because of their high fluorescence quantum yield, wide spectrum range, and strong absorption and emission wavelengths in the visible and near-infrared areas. Because of these qualities, cyanine dyes are excellent choices for imaging and detecting applications. An important method in nucleotide labeling is the use of cyanine dyes to label DNA or RNA. To achieve high-sensitivity and high-specificity detection and imaging, cyanine dye-labeled nucleotide probes can be employed in methods including fluorescence microscopy, flow cytometry, and fluorescence in situ hybridization (FISH).
