Iowa Black FQ Phosphoramidite | CAS 852203-68-0

Name: Iowa Black FQ Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R10-0036
Category	Other Quencher
Molecular Formula	C50H55N6O7P
Molecular Weight	882.98

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Product Introduction

Iowa Black FQ Phosphoramidite is a dark quencher reagent used in oligonucleotide synthesis. It contains an Iowa Black FQ non-fluorescent chromophore attached to a phosphoramidite moiety, enabling efficient incorporation at the 5' end of DNA or RNA sequences during automated solid-phase synthesis. It efficiently quenches fluorescence in the 420-620 nm range via Förster resonance energy transfer (FRET), making it ideal for dual-labeled probe synthesis such as TaqMan probes, molecular beacons, and other real-time PCR applications.

Chemical Information

Chemical Information

Synonyms	Phosphoramidous acid, bis(1-methylethyl)-, 2-[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl][4-[(4-nitro-1-naphthalenyl)azo]phenyl]amino]ethyl 2-cyanoethyl ester; 2-((2-(Bis(4-methoxyphenyl)(phenyl)methoxy)ethyl)(4-((4-nitronaphthalen-1-yl)diazenyl)phenyl)amino)ethyl (2-cyanoethyl) diisopropylphosphoramidite
SMILES	CC(N(C(C)C)P(OCCC#N)OCCN(CCOC(C1=CC=C(OC)C=C1)(C2=CC=C(OC)C=C2)C3=CC=CC=C3)C4=CC=C(N=NC5=C6C=CC=CC6=C([N+]([O-])=O)C=C5)C=C4)C
InChI	InChI=1S/C50H55N6O7P/c1-37(2)55(38(3)4)64(62-34-12-31-51)63-36-33-54(43-23-21-42(22-24-43)52-53-48-29-30-49(56(57)58)47-16-11-10-15-46(47)48)32-35-61-50(39-13-8-7-9-14-39,40-17-25-44(59-5)26-18-40)41-19-27-45(60-6)28-20-41/h7-11,13-30,37-38H,12,32-36H2,1-6H3
InChIKey	HNNXZGIKFPGCSE-UHFFFAOYSA-N
Boiling Point	903.5±65.0 °C at 760 mmHg