Iowa Black RQ Alkyne

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Iowa Black RQ Alkyne

Iowa Black RQ Alkyne

Catalog Number A20-0048
Category Alkynes
Molecular Formula C26H21N3O4
Molecular Weight 439.47
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Product Introduction

Iowa Black RQ Alkyne is a dark quencher reagent used for bioorthogonal click chemistry. It contains an Iowa Black RQ non-fluorescent chromophore conjugated to an alkyne functional group. The alkyne moiety enables copper-catalyzed or strain-promoted azide-alkyne cycloaddition with azide-functionalized molecules. It efficiently quenches fluorescence in the 550-750 nm range via Förster resonance energy transfer (FRET), making it ideal for dual-labeled probe synthesis and bioconjugation applications.

  • Chemical Information

Chemical Information

Synonyms 2-((9,10-Dioxo-4-(phenylamino)-9,10-dihydroanthracen-1-yl)amino)ethyl prop-2-yn-1-ylcarbamate
SMILES O=C(C1=C(C2=O)C=CC=C1)C(C2=C(C=C3)NC4=CC=CC=C4)=C3NCCOC(NCC#C)=O
InChI InChI=1S/C26H21N3O4/c1-2-14-28-26(32)33-16-15-27-20-12-13-21(29-17-8-4-3-5-9-17)23-22(20)24(30)18-10-6-7-11-19(18)25(23)31/h1,3-13,27,29H,14-16H2,(H,28,32)
InChIKey XOXYVVLSKJNXDT-UHFFFAOYSA-N

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