Propargyl-PEG2-NHBoc | 869310-84-9

Propargyl-PEG2-NHBoc, a versatile chemical linker, finds applications in diverse bio-conjugation and chemical biology endeavors. Explore its key applications with elevated perplexity and burstiness:

Bio-conjugation: Employing Propargyl-PEG2-NHBoc facilitates the intricate linking of biomolecules through click chemistry, enabling in-depth exploration of protein-protein interactions. This linker plays a pivotal role in anchoring proteins, peptides, or biomolecules onto surfaces or other molecules for bioanalytical purposes. The incorporation of a PEG spacer mitigates steric hindrance, ensuring precise and efficient conjugation.

Drug Delivery Systems: In the sphere of drug delivery research, Propargyl-PEG2-NHBoc serves as a valuable tool for tailoring nanoparticles or drug compounds to achieve targeted delivery. The inclusion of a PEG moiety enhances the solubility and biocompatibility of drug carriers, prolonging their circulation within the body. Conjugating drugs with Propargyl-PEG2-NHBoc allows for localized delivery, minimizing side effects and augmenting therapeutic efficacy.

Surface Functionalization: Leveraging Propargyl-PEG2-NHBoc enables the functionalization of surfaces for biosensing or cell culture applications. By modifying surfaces with this linker, researchers can immobilize biomolecules such as enzymes, antibodies, or DNA, creating highly specific and sensitive detection platforms. This advancement facilitates the development of sophisticated diagnostic tools and diverse cellular interaction studies.

Proteomics and Protein Labeling: Utilizing Propargyl-PEG2-NHBoc for protein labeling with fluorescent tags or affinity handles broadens avenues for proteomics research. The click chemistry reaction offers a streamlined and effective approach for attaching probes to target proteins. This technique is indispensable for tracking protein localization, investigating protein dynamics, or conducting pull-down assays, illuminating the intricate world of proteomics.