Iowa Black RQ dT Phosphoramidite

Name: Iowa Black RQ dT Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R10-0050
Category	Other Quencher
Molecular Formula	C71H79N8O13P
Molecular Weight	1283.43

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Product Introduction

Iowa Black RQ dT Phosphoramidite is a dark quencher reagent used in oligonucleotide synthesis. It contains an Iowa Black RQ non-fluorescent chromophore attached to a thymidine (dT) phosphoramidite, enabling site-specific incorporation within the oligonucleotide sequence. It efficiently quenches fluorescence in the 500-700 nm range via Förster resonance energy transfer (FRET), making it ideal for dual-labeled probe synthesis such as TaqMan probes, molecular beacons, and other real-time PCR applications.

Chemical Information

Chemical Information

Synonyms	2-((9,10-Dioxo-4-(phenylamino)-9,10-dihydroanthracen-1-yl)amino)ethyl (6-((E)-3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylamido)hexyl)carbamate
SMILES	CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@H](N2C=C(/C=C/C(NCCCCCCNC(OCCNC3=C(C(C(C=CC=C4)=C4C5=O)=O)C5=C(NC6=CC=CC=C6)C=C3)=O)=O)C(NC2=O)=O)O[C@@H]1COC(C7=CC=C(OC)C=C7)(C8=CC=CC=C8)C9=CC=C(OC)C=C9
InChI	InChI=1S/C71H79N8O13P/c1-47(2)79(48(3)4)93(90-42-19-38-72)92-60-44-63(91-61(60)46-89-71(50-20-11-9-12-21-50,51-27-31-54(86-5)32-28-51)52-29-33-55(87-6)34-30-52)78-45-49(68(83)77-69(78)84)26-37-62(80)74-39-17-7-8-18-40-75-70(85)88-43-41-73-58-35-36-59(76-53-22-13-10-14-23-53)65-64(58)66(81)56-24-15-16-25-57(56)67(65)82/h9-16,20-37,45,47-48,60-61,63,73,76H,7-8,17-19,39-44,46H2,1-6H3,(H,74,80)(H,75,85)(H,77,83,84)/b37-26+/t60-,61+,63+,93?/m0/s1
InChIKey	AJBYXZKWVZPYKM-NMHDVTSCSA-N