5-HEX Pro Phosphoramidite

Name: 5-HEX Pro Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R10-0026
Category	Phosphoramidites
Molecular Formula	C72H77Cl6N4O14P
Molecular Weight	1466.10

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Product Introduction

5-HEX Pro Phosphoramidite is a fluorescent labeling reagent used in oligonucleotide synthesis. It contains a 5-carboxy-2',4,4',5',7,7'-hexachlorofluorescein (5-HEX) fluorophore attached to a hydroxyprolinol-based phosphoramidite moiety. The hydroxyprolinol linker provides a rigid, non-nucleosidic scaffold for efficient incorporation of the HEX label at the 5' end of DNA sequences during automated solid-phase synthesis. It is commonly used in multiplex PCR, DNA sequencing, and fragment analysis applications.

Chemical Information

Chemical Information

Synonyms	5-Hexachloro-Fluorescein Pro Phosphoramidite; HEX Phosphoramidite, 5-isomer (hydroxyprolinol); Hexachloro Phosphoramidite, 5-isomer (hydroxyprolinol); 5-((6-((2S,4R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)pyrrolidin-1-yl)-6-oxohexyl)carbamoyl)-2',4,4',5',7,7'-hexachloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
SMILES	COC(C=C1)=CC=C1C(C2=CC=CC=C2)(OC[C@@H]3C[C@H](CN3C(CCCCCNC(C4=CC(Cl)=C(C56C(C=C7Cl)=C(OC8=C5C=C(Cl)C(OC(C(C)(C)C)=O)=C8Cl)C(Cl)=C7OC(C(C)(C)C)=O)C(C(O6)=O)=C4Cl)=O)=O)OP(N(C(C)C)C(C)C)OCCC#N)C9=CC=C(C=C9)OC
InChI	InChI=1S/C72H77Cl6N4O14P/c1-40(2)82(41(3)4)97(91-33-19-31-79)96-48-34-45(39-90-71(42-20-15-13-16-21-42,43-23-27-46(88-11)28-24-43)44-25-29-47(89-12)30-26-44)81(38-48)55(83)22-17-14-18-32-80-65(84)49-35-52(73)57-56(58(49)76)66(85)95-72(57)50-36-53(74)63(93-67(86)69(5,6)7)59(77)61(50)92-62-51(72)37-54(75)64(60(62)78)94-68(87)70(8,9)10/h13,15-16,20-21,23-30,35-37,40-41,45,48H,14,17-19,22,32-34,38-39H2,1-12H3,(H,80,84)/t45-,48+,97?/m0/s1
InChIKey	KXANPIGIVIGYEX-UMUCQOALSA-N