TFA-Hexylaminolinker Phosphoramidite | 133975-85-6
Catalog Number | R10-0011 |
Category | DNA Stains |
Molecular Formula | C17H31F3N3O3P |
Molecular Weight | 413.42 |
Catalog Number | Size | Price | Quantity |
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R10-0011 | -- | $-- |
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Product Introduction
TFA-Hexylaminolinker Phosphoramidite is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required.
Chemical Information |
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Synonyms | TFA-aminolinker C6 phosphoramidite; 2-Cyanoethyl (6-(2,2,2-trifluoroacetamido)hexyl) diisopropylphosphoramidite; 6-(N-Trifluoroacetamido)hexyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-Amino-Modifier C6-TFA CE Phosphoramidite; Trifluoroacetyl-hexylamine-linker Phosphoramidite; 5'-Amino-Modifier C6-TFA CEP; Trifluoroacetyl cyanoethyl phosphoramidite amino-linker; C6 TFA linker amidite; TFA-Hexylaminolinker Amidite |
Purity | ≥90% |
IUPAC Name | N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]-2,2,2-trifluoroacetamide |
Canonical SMILES | CC(C)N(C(C)C)P(OCCCCCCNC(=O)C(F)(F)F)OCCC#N |
InChI | InChI=1S/C17H31F3N3O3P/c1-14(2)23(15(3)4)27(26-13-9-10-21)25-12-8-6-5-7-11-22-16(24)17(18,19)20/h14-15H,5-9,11-13H2,1-4H3,(H,22,24) |
InChI Key | SMMKTKILBQHSFL-UHFFFAOYSA-N |
Solubility | Soluble in Acetonitrile, DCM, THF |
Appearance | Colorless, light yellow solid |
Boiling Point | 433.7±45.0 °C at 760 mmHg |
- Product Specification
Storage | Store at -20 °C |
Computed Properties | |
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XLogP3 | 3.4 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 14 |
Exact Mass | 413.20551334 g/mol |
Monoisotopic Mass | 413.20551334 g/mol |
Topological Polar Surface Area | 74.6Ų |
Heavy Atom Count | 27 |
Formal Charge | 0 |
Complexity | 459 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
Patents
Publication Number | Title | Priority Date |
---|---|---|
WO-2022266658-A1 | Methods of preparing bivalent molecules | 2021-06-17 |
WO-2021195295-A1 | Bifunctional molecules and methods of using thereof | 2020-03-24 |
US-2021198671-A1 | Protected antibody-drug and aptamer-drug conjugates | 2019-12-27 |
WO-2021004379-A1 | Fluorescently labeled nucleic acid and synthesis method therefor | 2019-07-05 |
WO-2020186174-A1 | Methods and systems for processing or analyzing oligonucleotide encoded molecules | 2019-03-14 |
Applications of Fluorescent Probes & Dyes
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