5-TET Pro Phosphoramidite

Name: 5-TET Pro Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R10-0024
Category	Phosphoramidites
Molecular Formula	C72H79Cl4N4O14P
Molecular Weight	1397.21

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Product Introduction

5-TET Pro Phosphoramidite is a fluorescent labeling reagent used in oligonucleotide synthesis. It contains a 5-carboxy-4,7,2',7'-tetrachlorofluorescein (5-TET) fluorophore attached to a hydroxyprolinol-based phosphoramidite moiety. The hydroxyprolinol linker provides a rigid, non-nucleosidic scaffold for efficient incorporation of the TET label at the 5' end of DNA sequences during automated solid-phase synthesis. It is commonly used in multiplex PCR, DNA sequencing, and fragment analysis applications.

Chemical Information

Chemical Information

Synonyms	5-Tetrachloro-Fluorescein Pro Phosphoramidite; TET Phosphoramidite, 5-isomer (hydroxyprolinol); Tetrachloro Phosphoramidite, 5-isomer (hydroxyprolinol); 5-((6-((2S,4R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)pyrrolidin-1-yl)-6-oxohexyl)carbamoyl)-2',4,7,7'-tetrachloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
SMILES	COC(C=C1)=CC=C1C(C2=CC=CC=C2)(OC[C@@H]3C[C@H](CN3C(CCCCCNC(C4=CC(Cl)=C(C56C(C=C7Cl)=C(OC8=C5C=C(Cl)C(OC(C(C)(C)C)=O)=C8)C=C7OC(C(C)(C)C)=O)C(C(O6)=O)=C4Cl)=O)=O)OP(N(C(C)C)C(C)C)OCCC#N)C9=CC=C(C=C9)OC
InChI	InChI=1S/C72H79Cl4N4O14P/c1-42(2)80(43(3)4)95(89-33-19-31-77)94-50-34-47(41-88-71(44-20-15-13-16-21-44,45-23-27-48(86-11)28-24-45)46-25-29-49(87-12)30-26-46)79(40-50)61(81)22-17-14-18-32-78-65(82)51-35-56(75)63-62(64(51)76)66(83)93-72(63)52-36-54(73)59(91-67(84)69(5,6)7)38-57(52)90-58-39-60(55(74)37-53(58)72)92-68(85)70(8,9)10/h13,15-16,20-21,23-30,35-39,42-43,47,50H,14,17-19,22,32-34,40-41H2,1-12H3,(H,78,82)/t47-,50+,95?/m0/s1
InChIKey	XZTRNJIAZQICEA-MZXSDKSGSA-N