TCO TEG Phosphoramidite

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TCO TEG Phosphoramidite

TCO TEG Phosphoramidite

Catalog Number R10-0048
Category Phosphoramidites
Molecular Formula C26H48N3O7P
Molecular Weight 545.66
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Product Introduction

TCO TEG Phosphoramidite is a click chemistry reagent used in oligonucleotide synthesis. It contains a trans-cyclooctene (TCO) functional group attached to a phosphoramidite via a triethylene glycol (TEG) linker. The TCO group enables highly efficient and rapid bioorthogonal inverse electron demand Diels-Alder (IEDDA) reactions with tetrazine-functionalized molecules, allowing selective labeling and bioconjugation of oligonucleotides under mild, copper-free conditions.

  • Chemical Information

  • Product Specification

Chemical Information

Synonyms (R,E)-Cyclooct-4-en-1-yl (2-(2-(2-(2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethoxy)ethoxy)ethoxy)ethyl)carbamate
SMILES N#CCCOP(N(C(C)C)C(C)C)OCCOCCOCCOCCNC(O[C@H]1CC/C=C/CCC1)=O
InChI InChI=1S/C26H48N3O7P/c1-23(2)29(24(3)4)37(34-15-10-13-27)35-22-21-33-20-19-32-18-17-31-16-14-28-26(30)36-25-11-8-6-5-7-9-12-25/h5-6,23-25H,7-12,14-22H2,1-4H3,(H,28,30)/b6-5+/t25-,37?/m0/s1
InChIKey RFGSLOPZPOFQDG-SWTBTQGLSA-N

Product Specification

Storage Store at -20 °C

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