6-TAMRA cyclohexyl phosphoramidite

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6-TAMRA cyclohexyl phosphoramidite

6-TAMRA cyclohexyl phosphoramidite

Catalog Number R10-0028
Category Phosphoramidites
Molecular Formula C40H50N5O6P
Molecular Weight 727.83
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Product Introduction

6-TAMRA cyclohexyl phosphoramidite is a fluorescent labeling reagent used in oligonucleotide synthesis. It contains a 6-carboxytetramethylrhodamine (6-TAMRA) fluorophore attached to a cyclohexyl phosphoramidite moiety, enabling incorporation of the TAMRA label at the 5' end of DNA or RNA sequences during automated solid-phase synthesis. It is widely used in molecular biology applications including DNA sequencing, real-time PCR, fluorescence resonance energy transfer (FRET) studies, and dual-labeled probe synthesis.

  • Chemical Information

  • Product Specification

Chemical Information

Synonyms TAMRA phosphoramidite, 6-isomer; 6-TAMRA phosphoramidite; 4-(3',6'-Bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamido)cyclohexyl (2-cyanoethyl) diisopropylphosphoramidite; 6-TAMRA Phosphoramidite ACH
IUPAC Name N-[4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxycyclohexyl]-3',6'-bis(dimethylamino)-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxamide
SMILES CC(C)N(C(C)C)P(OCCC#N)OC1CCC(CC1)NC(=O)C2=CC3=C(C=C2)C(=O)OC34C5=C(C=C(C=C5)N(C)C)OC6=C4C=CC(=C6)N(C)C
InChI InChI=1S/C40H50N5O6P/c1-25(2)45(26(3)4)52(48-21-9-20-41)51-31-15-11-28(12-16-31)42-38(46)27-10-17-32-35(22-27)40(50-39(32)47)33-18-13-29(43(5)6)23-36(33)49-37-24-30(44(7)8)14-19-34(37)40/h10,13-14,17-19,22-26,28,31H,9,11-12,15-16,21H2,1-8H3,(H,42,46)
InChIKey WAXFLCDSTVMRSD-UHFFFAOYSA-N
Solubility Soluble in Acetonitrile, DCM
Appearance Red solid

Product Specification

Storage Store at -20 °C

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