6-ROX Pro Phosphoramidite

Name: 6-ROX Pro Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R10-0030
Category	Phosphoramidites
Molecular Formula	C74H85N6O10P
Molecular Weight	1249.50

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Product Introduction

6-ROX Pro Phosphoramidite is a fluorescent labeling reagent used in oligonucleotide synthesis. It contains a 6-carboxy-X-rhodamine (6-ROX) fluorophore attached to a hydroxyprolinol-based phosphoramidite moiety. The hydroxyprolinol linker provides a rigid, non-nucleosidic scaffold for efficient incorporation of the ROX label at the 5' end of DNA or RNA sequences during automated solid-phase synthesis. It is commonly used in multiplex PCR, DNA sequencing, fragment analysis, and fluorescence resonance energy transfer (FRET) applications.

Chemical Information

Chemical Information

Synonyms	6-ROX Phosphoramidite (hydroxyprolinol); ROX Pro Phosphoramidite, 6-isomer; ROX Phosphoramidite, 6-isomer (hydroxyprolinol)
SMILES	N#CCCOP(N(C(C)C)C(C)C)O[C@@H](C1)C[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N1C(CCCCCNC(C5=CC=C(C6=C5)C(OC76C8=C(C9=C%10N(CCCC%10=C8)CCC9)OC%11=C7C=C%12CCCN%13CCCC%11=C%12%13)=O)=O)=O
InChI	InChI=1S/C74H85N6O10P/c1-48(2)80(49(3)4)91(87-41-17-35-75)90-59-45-56(47-86-73(53-20-9-7-10-21-53,54-26-30-57(84-5)31-27-54)55-28-32-58(85-6)33-29-55)79(46-59)66(81)24-11-8-12-36-76-71(82)52-25-34-60-63(44-52)74(89-72(60)83)64-42-50-18-13-37-77-39-15-22-61(67(50)77)69(64)88-70-62-23-16-40-78-38-14-19-51(68(62)78)43-65(70)74/h7,9-10,20-21,25-34,42-44,48-49,56,59H,8,11-19,22-24,36-41,45-47H2,1-6H3,(H,76,82)/t56-,59+,91?/m0/s1
InChIKey	JZRVASIEKRDEKG-KQQXPPNUSA-N