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Pyrene-dU-CE Phosphoramidite | CAS 199920-17-7
| Catalog Number | R10-0010 |
| Category | Phosphoramidites |
| Molecular Formula | C57H55N4O8P |
| Molecular Weight | 955.04 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R10-0010 | -- | -- |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Pyrene-dU-CE phosphoramidite, a key element in the creation of fluorescent oligonucleotides, boasts unique chemical properties that lend themselves to targeted detection of RNA or DNA sequences. Widely employed in both disease diagnosis and drug discovery, this highly potent compound serves as an engine of innovation in the ever-evolving field of molecular biology.
Chemical Information
Product Specification
| Synonyms | Pyrene phosphoramidite dU;5'-Dimethoxytrityl-5-(pyren-1-yl-ethynyl)-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
| Purity | NMR 1H (95%), 31P, HPLC-MS |
| IUPAC Name | 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-[2,4-dioxo-5-(2-pyren-1-ylethynyl)pyrimidin-1-yl]oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile |
| Canonical SMILES | CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C#CC6=C7C=CC8=CC=CC9=C8C7=C(C=C9)C=C6 |
| InChI | InChI=1S/C57H55N4O8P/c1-37(2)61(38(3)4)70(67-33-11-32-58)69-50-34-52(60-35-43(55(62)59-56(60)63)21-17-39-16-18-42-20-19-40-12-10-13-41-22-31-49(39)54(42)53(40)41)68-51(50)36-66-57(44-14-8-7-9-15-44,45-23-27-47(64-5)28-24-45)46-25-29-48(65-6)30-26-46/h7-10,12-16,18-20,22-31,35,37-38,50-52H,11,33-34,36H2,1-6H3,(H,59,62,63)/t50-,51+,52+,70?/m0/s1 |
| InChIKey | UPMNDVODTLNHCL-UTNLAKSGSA-N |
| Solubility | good in dichloromethane and acetonitrile |
| Appearance | yellowish foam |
| ε, L⋅mol-1⋅cm-1 | 12600; 21900; 16000; 14200 |
| Fluorescence Quantum Yield | ~0.1 |
| Excitation | 260; 282; 365; 392 |
| Emission | 460 |
| Storage | Store at -20°C |
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