6-Hexynoic acid alkyne C6-dT Phosphoramidite

Name: 6-Hexynoic acid alkyne C6-dT Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R10-0051
Category	Alkynes
Molecular Formula	C54H69N6O10P
Molecular Weight	993.15

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Product Introduction

6-Hexynoic acid alkyne C6-dT Phosphoramidite is a click chemistry reagent used in oligonucleotide synthesis. It contains a terminal alkyne group attached to a thymidine (dT) phosphoramidite via a 6-hexynoic acid linker, enabling site-specific incorporation within the oligonucleotide sequence. The terminal alkyne allows bioorthogonal click chemistry reactions, particularly copper-catalyzed or strain-promoted azide-alkyne cycloaddition, for post-synthetic labeling and bioconjugation applications.

Chemical Information

Chemical Information

Synonyms	(2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-((E)-3-((6-(hex-5-ynamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
SMILES	CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@H](N2C=C(/C=C/C(NCCCCCCNC(CCCC#C)=O)=O)C(NC2=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5
InChI	InChI=1S/C54H69N6O10P/c1-8-9-13-21-49(61)56-33-16-10-11-17-34-57-50(62)31-22-41-37-59(53(64)58-52(41)63)51-36-47(70-71(68-35-18-32-55)60(39(2)3)40(4)5)48(69-51)38-67-54(42-19-14-12-15-20-42,43-23-27-45(65-6)28-24-43)44-25-29-46(66-7)30-26-44/h1,12,14-15,19-20,22-31,37,39-40,47-48,51H,9-11,13,16-18,21,33-36,38H2,2-7H3,(H,56,61)(H,57,62)(H,58,63,64)/b31-22+/t47-,48+,51+,71?/m0/s1
InChIKey	DUYYTZOIEAPBNF-GHEIHOOQSA-N