Thionin perchlorate

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Thionin perchlorate

Thionin perchlorate | 25137-58-0

Catalog Number A19-0032
Category DNA Stains
Molecular Formula C12H10ClN3O4S
Molecular Weight 327.74
Catalog Number Size Price Quantity
A19-0032 -- $--

Product Introduction

Thionin perchlorate is a general nuclear stain for chromatin and mucin.

Chemical Information

Synonyms 3,7-Diaminophenothiazin-5-ium perchlorate
IUPAC Name (7-aminophenothiazin-3-ylidene)azanium;perchlorate
Canonical SMILES C1=CC2=C(C=C1N)SC3=CC(=[NH2+])C=CC3=N2.[O-]Cl(=O)(=O)=O
InChI InChI=1S/C12H9N3S.ClHO4/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;2-1(3,4)5/h1-6,13H,14H2;(H,2,3,4,5)
InChI Key GRBYIIMHBWPSQG-UHFFFAOYSA-N
Appearance Solid Powder
  • Product Specification
  • Application
Signal Warning
GHS Hazard Statements H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

Thionin perchlorate is a chemical compound known for its versatile applications in both scientific research and industry. Here are some key applications of thionin perchlorate:

Staining and Microscopy: Thionin perchlorate is widely used as a staining agent in various microscopy techniques. It binds to nucleic acids, allowing for the differentiation of DNA and RNA in tissue sections and cell samples. This makes it an essential tool in histology and cytology for studying cellular structures and pathology.

Electrochemical Sensors: Thionin perchlorate is employed in the development of electrochemical sensors due to its redox properties. It can be used to coat electrode surfaces, enhancing the sensitivity and selectivity of sensors for detecting various analytes, such as glucose, heavy metals, and environmental contaminants. This application is crucial for creating efficient and accurate diagnostic tools.

DNA and RNA Research: In molecular biology, thionin perchlorate is used in various protocols for the visualization and quantification of nucleic acids. It can be employed in gel electrophoresis as well as in spectrophotometry to measure nucleic acid concentrations. This aids researchers in accurately analyzing genetic material for cloning, sequencing, and other genetic studies.

Antimicrobial Studies: Thionin perchlorate has demonstrated antimicrobial properties, making it useful in microbiological research. It can be used to study the bactericidal and fungicidal effects on various microorganisms. Researchers can leverage this compound to explore new antimicrobial agents and understand mechanisms of microbial resistance.

Computed Properties

Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 0
Exact Mass 327.0080547 g/mol
Monoisotopic Mass 327.0080547 g/mol
Topological Polar Surface Area 164Ų
Heavy Atom Count 21
Formal Charge 0
Complexity 484
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
EP-3374416-A1 Photoalignment materials 2015-11-11
EP-3374467-A1 Compositions of photo-alignable materials 2015-11-11
EP-3374467-B1 Compositions of photo-alignable materials 2015-11-11
US-10696795-B2 Photoaligning materials 2015-11-11
US-2018319939-A1 Photoaligning materials 2015-11-11
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