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Biotin-11-UTP
| Catelog Number | A19-0072 |
| Category | DNA Stains |
| Molecular Formula | C28H45N6O18P3S (free acid) |
| Molecular Weight | 878.67 (free acid) |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A19-0072 | -- | $-- |
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Product Introduction
Biotin-11-UTP is a valuable nucleotide analogue widely used in biomedicine research for RNA labeling and detection. It can be enzymatically incorporated into RNA molecules during transcription, leading to biotin-labeled RNA that can be easily detected or purified using avidin-biotin interaction. Biotin-11-UTP is also used in molecular diagnostics for detecting infectious diseases and genetic disorders.
Chemical Information |
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|---|---|
| Synonyms | Biotin-X-5-Aminoallyl-UTP; Biotin-X-5-Aminoallyl-uridine-5'-triphosphate, Triethylammonium salt |
| Purity | ≥ 95% by HPLC |
| IUPAC Name | trilithium;[[[(1R,2R,3S,4R)-4-[5-[3-[6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoylamino]prop-1-ynyl]-2,4-dioxopyrimidin-1-yl]-2,3-dihydroxycyclopentyl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate |
| Canonical SMILES | [Li+].[Li+].[Li+].C1C(C(C(C1N2C=C(C(=O)NC2=O)C#CCNC(=O)CCCCCNC(=O)CCCCC3C4C(CS3)NC(=O)N4)O)O)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-] |
| InChI | InChI=1S/C29H45N6O17P3S.3Li/c36-22(9-2-1-5-11-30-23(37)10-4-3-8-21-24-19(16-56-21)32-28(41)33-24)31-12-6-7-17-14-35(29(42)34-27(17)40)20-13-18(25(38)26(20)39)15-50-54(46,47)52-55(48,49)51-53(43,44)45;;;/h14,18-21,24-26,38-39H,1-5,8-13,15-16H2,(H,30,37)(H,31,36)(H,46,47)(H,48,49)(H2,32,33,41)(H,34,40,42)(H2,43,44,45);;;/q;3*+1/p-3/t18-,19+,20-,21+,24+,25-,26+;;;/m1.../s1 |
| InChI Key | ZBJFRSKZQRNXSZ-MPAUVNFJSA-K |
| Solubility | Good in water |
| Appearance | sterile clear aequous solution in 10 mM Tris-HCl |
Product Specification |
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|---|---|
| Storage | Storage: 12 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks. Avoid excessive freeze-thaw cycles. |
Computed Properties | |
|---|---|
| Hydrogen Bond Donor Count | 8 |
| Hydrogen Bond Acceptor Count | 18 |
| Rotatable Bond Count | 21 |
| Exact Mass | 892.2020114 g/mol |
| Monoisotopic Mass | 892.2020114 g/mol |
| Topological Polar Surface Area | 383Ų |
| Heavy Atom Count | 59 |
| Formal Charge | 0 |
| Complexity | 1770 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 7 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 4 |
| Compound Is Canonicalized | Yes |
Applications of Fluorescent Probes & Dyes
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