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Thionin perchlorate | CAS 25137-58-0
| Catalog Number | A19-0032 |
| Category | DNA Stains |
| Molecular Formula | C12H10ClN3O4S |
| Molecular Weight | 327.74 |
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Product Introduction
Thionin perchlorate is a general nuclear stain for chromatin and mucin.
Chemical Information
Product Specification
Application
Computed Properties
Patents
| Synonyms | 3,7-Diaminophenothiazin-5-ium perchlorate |
| IUPAC Name | (7-aminophenothiazin-3-ylidene)azanium;perchlorate |
| Canonical SMILES | C1=CC2=C(C=C1N)SC3=CC(=[NH2+])C=CC3=N2.[O-]Cl(=O)(=O)=O |
| InChI | InChI=1S/C12H9N3S.ClHO4/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;2-1(3,4)5/h1-6,13H,14H2;(H,2,3,4,5) |
| InChIKey | GRBYIIMHBWPSQG-UHFFFAOYSA-N |
| Appearance | Solid Powder |
| Signal | Warning |
| GHSHazardStatements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Thionin perchlorate is a chemical compound known for its versatile applications in both scientific research and industry. Here are some key applications of thionin perchlorate:
Staining and Microscopy: Thionin perchlorate is widely used as a staining agent in various microscopy techniques. It binds to nucleic acids, allowing for the differentiation of DNA and RNA in tissue sections and cell samples. This makes it an essential tool in histology and cytology for studying cellular structures and pathology.
Electrochemical Sensors: Thionin perchlorate is employed in the development of electrochemical sensors due to its redox properties. It can be used to coat electrode surfaces, enhancing the sensitivity and selectivity of sensors for detecting various analytes, such as glucose, heavy metals, and environmental contaminants. This application is crucial for creating efficient and accurate diagnostic tools.
DNA and RNA Research: In molecular biology, thionin perchlorate is used in various protocols for the visualization and quantification of nucleic acids. It can be employed in gel electrophoresis as well as in spectrophotometry to measure nucleic acid concentrations. This aids researchers in accurately analyzing genetic material for cloning, sequencing, and other genetic studies.
Antimicrobial Studies: Thionin perchlorate has demonstrated antimicrobial properties, making it useful in microbiological research. It can be used to study the bactericidal and fungicidal effects on various microorganisms. Researchers can leverage this compound to explore new antimicrobial agents and understand mechanisms of microbial resistance.
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 0 |
| Exact Mass | 327.0080547 g/mol |
| Monoisotopic Mass | 327.0080547 g/mol |
| Topological Polar Surface Area | 164Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 484 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3374416-A1 | Photoalignment materials | 2015-11-11 |
| EP-3374467-A1 | Compositions of photo-alignable materials | 2015-11-11 |
| EP-3374467-B1 | Compositions of photo-alignable materials | 2015-11-11 |
| US-10696795-B2 | Photoaligning materials | 2015-11-11 |
| US-2018319939-A1 | Photoaligning materials | 2015-11-11 |
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