SIMA phosphoramidite, 6-isomer | 1411797-05-1

Catalog Number	A07-0050
Category	RNA/DNA Labeling
Molecular Formula	C58H64N3Cl2O10P
Molecular Weight	1065.02

Catalog Number	Size	Price	Quantity
A07-0050	--	$--

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Product Introduction

SIMA (dichloro-diphenyl-fluorescein) is a xanthene dye with spectral characteristics similar to those of HEX but with a higher quantum yield. SIMA phosphoramidite is used in oligonucleotide synthesis to produce fluorescently labeled primers and hybridization probes for quantitative PCR.

Chemical Information
Synonyms	6-(4,7-Dichloro-2',7'-diphenyl-3',6'-dipivaloylfluorescein-6-carboxamido)-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-4,7-dichloro-3-oxo-2',7'-diphenylspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[10-[Bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-4,7-dichloro-3-oxo-2',7'-diphenylspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); SIMA; SIMA phosphoramidite, 6-isomer
IUPAC Name	[4,7-dichloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxo-2',7'-diphenylspiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
Canonical SMILES	CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC(=C2C(=C1Cl)C3(C4=C(C=C(C(=C4)C5=CC=CC=C5)OC(=O)C(C)(C)C)OC6=C3C=C(C(=C6)OC(=O)C(C)(C)C)C7=CC=CC=C7)OC2=O)Cl)OCCC#N
InChI	InChI=1S/C58H64Cl2N3O10P/c1-35(2)63(36(3)4)74(69-29-21-26-61)68-28-20-12-11-19-27-62-52(64)41-32-44(59)49-50(51(41)60)58(73-53(49)65)42-30-39(37-22-15-13-16-23-37)45(71-54(66)56(5,6)7)33-47(42)70-48-34-46(72-55(67)57(8,9)10)40(31-43(48)58)38-24-17-14-18-25-38/h13-18,22-25,30-36H,11-12,19-21,27-29H2,1-10H3,(H,62,64)
InChI Key	WPCMEEMVKXSQGE-UHFFFAOYSA-N
Solubility	Soluble in acetonitrile and DCM
Appearance	White Powder