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6-Tetrachloro-Fluorescein Phosphoramidite | CAS 877049-90-6
| Catalog Number | A07-0060 |
| Category | RNA/DNA Labeling |
| Molecular Formula | C46H54N3O10Cl4P |
| Molecular Weight | 981.72 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
6-Tetrachloro-Fluorescein Phosphoramidite is a reactive fluorophore that serves as a precursor in oligonucleotide labeling, featuring a tetrachloro-modified fluorescein core. This compound exhibits characteristic excitation and emission profiles that are integral to fluorescence resonance energy transfer (FRET) applications and nucleic acid hybridization assays. Its phosphoramidite functionality enables efficient incorporation into DNA or RNA strands during automated synthesis, facilitating the development of fluorescently labeled probes for advanced bioimaging and diagnostic assays.
Chemical Information
Product Specification
Chemical Information
| Synonyms | DyLight TET CEP; Propanoic acid, 2,2-dimethyl-, 6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,7,7'-tetrachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; 6-TET Phosphoramidite; TET phosphoramidite, 6-isomer; 6-(4,7,2',7'-Tetrachloro-3',6'-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
| Purity | ≥95% |
| IUPAC Name | [2',4,7,7'-tetrachloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate |
| SMILES | CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC(=C2C(=C1Cl)C3(C4=CC(=C(C=C4OC5=CC(=C(C=C53)Cl)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)Cl)OC2=O)Cl)OCCC#N |
| InChI | InChI=1S/C46H54Cl4N3O10P/c1-25(2)53(26(3)4)64(59-19-15-16-51)58-18-14-12-11-13-17-52-40(54)27-20-32(49)37-38(39(27)50)46(63-41(37)55)28-21-30(47)35(61-42(56)44(5,6)7)23-33(28)60-34-24-36(31(48)22-29(34)46)62-43(57)45(8,9)10/h20-26H,11-15,17-19H2,1-10H3,(H,52,54) |
| InChIKey | RKVIHIDUTMZQEZ-UHFFFAOYSA-N |
| Appearance | White to off-white powder |
| Boiling Point | 895.1±65.0 °C at 760 mmHg |
Product Specification
| Storage | Store at -20 °C |
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