Alkyne dT phosphoramidite

Name: Alkyne dT phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	A19-0080
Category	DNA Stains
Molecular Formula	C48H56N5O9P
Molecular Weight	877.96

Inquiry

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Worldwide Delivery
Quality Assurance
24/7 Customer Service

Product Introduction

Alkyne dT phosphoramidite is a nucleoside phosphoramidite that features an alkyne moiety, enabling its use in bioorthogonal conjugation reactions. This compound is incorporated into oligonucleotides during solid-phase synthesis, allowing for subsequent labeling with azide-functionalized fluorescent dyes through a copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. Alkyne dT phosphoramidite is widely utilized in the development of fluorescently labeled DNA probes for applications in fluorescence microscopy, molecular tracking, and biosensing assays.

Chemical Information
Product Specification
Computed Properties

Chemical Information

Purity	NMR 1H, NMR 31P, HPLC-MS
IUPAC Name	5-[1-[(2R,5R)-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-5-methyloxolan-2-yl]-2,4-dioxopyrimidin-5-yl]pent-4-ynyl-oxo-(prop-2-ynylamino)azanium
SMILES	CC1C(CC(O1)N2C=C(C(=O)NC2=O)C#CCCC[N+](=O)NCC#C)OP(N(C(C)C)C(C)C)OCCC#N
InChI	InChI=1S/C26H37N6O6P/c1-7-14-28-31(35)15-10-8-9-12-22-18-30(26(34)29-25(22)33)24-17-23(21(6)37-24)38-39(36-16-11-13-27)32(19(2)3)20(4)5/h1,18-21,23-24H,8,10-11,14-17H2,2-6H3,(H-,28,29,33,34,35)/p+1/t21-,23?,24-,39?/m1/s1
InChIKey	QUPDQSRQEDVHPT-IAWAGCJASA-O
Solubility	Good in acetonitrile, DCM
Appearance	Off white solid

Product Specification

Mass Spec M+ Increment	437.1
Storage	Storage: 12 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks. Desiccate.

Computed Properties

XLogP3	2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	15
Exact Mass	561.25904495 g/mol
Monoisotopic Mass	561.25904495 g/mol
Topological Polar Surface Area	136Å²
Heavy Atom Count	39
Formal Charge	1
Complexity	1090
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes