Inquiry Basket
Hoechst 33258 Analog 6 | 129244-66-2
| Catalog Number | A19-0047 |
| Category | DNA Stains |
| Molecular Formula | C33H40N6O |
| Molecular Weight | 536.71 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A19-0047 | -- | $-- |
- Worldwide Delivery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Hoechst 33258 analog 6 is an analog of Hoechst 33258 that can be used for staining DNA as a blue fluorescent dye.
Chemical Information |
|
|---|---|
| Synonyms | 2,6-di-tert-butyl-4-[6-[6-(4-methylpiperazin-1-yl)-1-H-benzimidazol-2-yl]-1-H-benzimidazol-2-yl]phenol |
| Purity | ≥98% |
| Shelf Life | 2 years |
| Canonical SMILES | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C2=NC3=C(N2)C=C(C=C3)C4=NC5=C(N4)C=C(C=C5)N6CCN(CC6)C |
| InChI | InChI=1S/C33H40N6O/c1-32(2,3)23-16-21(17-24(29(23)40)33(4,5)6)31-35-25-10-8-20(18-27(25)36-31)30-34-26-11-9-22(19-28(26)37-30)39-14-12-38(7)13-15-39/h8-11,16-19,40H,12-15H2,1-7H3,(H,34,37)(H,35,36) |
| InChI Key | LXRWWFIBSFWADZ-UHFFFAOYSA-N |
| Appearance | Solid Powder |
- Product Specification
- Application
| Storage | Store at -20°C |
Hoechst 33258 Analog 6, a fluorescent dye widely utilized in diverse biological and clinical contexts, offers an array of applications showcased below:
Cell Nuclei Staining: Widely employed in fluorescence microscopy, Hoechst 33258 Analog 6 is a staple for staining cell nuclei. Emitting a vibrant blue fluorescence upon DNA binding, it enables researchers to vividly visualize and quantify nuclear morphology and DNA content. This pivotal application plays a vital role in cell cycle investigations, apoptosis assays, and chromosome analyses, shedding light on intricate cellular processes.
Live Cell Imaging: Renowned for its low toxicity and strong DNA affinity, Hoechst 33258 Analog 6 is a go-to option for live cell imaging. Research endeavors benefit from the ability to observe real-time cellular dynamics, including cell division, migration, and nuclear activities, without compromising cell viability significantly. This capability is especially crucial for dynamic studies in developmental biology and cancer research, offering a glimpse into the dynamic nature of living cells.
Flow Cytometry: Embraced in flow cytometry, Hoechst 33258 Analog 6 plays a pivotal role in analyzing cellular DNA content. Its usage allows for the discrimination of distinct cell populations based on their DNA content, facilitating cell cycle assessments and the identification of stem cells or specific subpopulations. This versatile application garners significance in both fundamental research and clinical diagnostics, aiding in unraveling the intricacies of cellular composition and function.
Genotoxicity Testing: Leveraged in genotoxicity assays, Hoechst 33258 Analog 6 serves as a valuable tool in detecting DNA damage induced by potential mutagens. By staining DNA, researchers can evaluate chromosomal aberrations, micronuclei formation, and other genotoxic effects under fluorescence microscopy. This critical function plays a pivotal role in assessing the safety and hazards of new chemicals and pharmaceuticals.
Applications of Fluorescent Probes & Dyes
Get More Product Details?
