Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 | 150956-93-7

Catelog Number	A18-0037
Category	Fluorescent Enzyme Substrates
Molecular Formula	C51H72N14O12S
Molecular Weight	1105.3

Catalog Number	Size	Price	Quantity
A18-0037	--	$--

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Product Introduction

Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. It is cleaved by MMP-1 and MMP-9 to release N-methylanthranilic acid (Nma), which is unquenched and its fluorescence can be used to quantify MMP activity.

Chemical Information
Synonyms	Matrix Metalloproteinase-1 Fluorogenic Substrate III; MMP-1 Fluorogenic Substrate III; (S)-N-((7S,10S,13S,16R,19S,22S)-13-((1H-imidazol-5-yl)methyl)-7-carbamoyl-23-cyclohexyl-19-ethyl-10-methyl-1-(2-(methylamino)phenyl)-16-((methylthio)methyl)-1,9,12,15,18,21-hexaoxo-2,8,11,14,17,20-hexaazatricosan-22-yl)-1-(2,4-dinitrophenyl)pyrrolidine-2-carboxamide
Purity	≥95%
Canonical SMILES	CCC(C(=O)NC(CSC)C(=O)NC(CC1=CN=CN1)C(=O)NC(C)C(=O)NC(CCCCNC(=O)C2=CC=CC=C2NC)C(=O)N)NC(=O)C(CC3CCCCC3)NC(=O)C4CCCN4C5=C(C=C(C=C5)[N+](=O)[O-])[N+](=O)[O-]
InChI	InChI=1S/C51H72N14O12S/c1-5-35(58-49(71)38(24-31-14-7-6-8-15-31)61-51(73)42-19-13-23-63(42)41-21-20-33(64(74)75)26-43(41)65(76)77)47(69)62-40(28-78-4)50(72)60-39(25-32-27-54-29-56-32)48(70)57-30(2)45(67)59-37(44(52)66)18-11-12-22-55-46(68)34-16-9-10-17-36(34)53-3/h9-10,16-17,20-21,26-27,29-31,35,37-40,42,53H,5-8,11-15,18-19,22-25,28H2,1-4H3,(H2,52,66)(H,54,56)(H,55,68)(H,57,70)(H,58,71)(H,59,67)(H,60,72)(H,61,73)(H,62,69)/t30-,35-,37-,38-,39-,40-,42-/m0/s1
InChI Key	ZXWDGVAWRUKOAR-IHGWQQAUSA-N