7-Ethoxy-4-trifluoromethylcoumarin | 115453-82-2

7-Ethoxy-4-trifluoromethylcoumarin, a versatile synthetic organic compound widely utilized in biological and chemical research, offers a plethora of applications.

Fluorescent Probes: Illuminating the field of molecular and cellular studies, 7-Ethoxy-4-trifluoromethylcoumarin acts as a radiant fluorescent probe, shining a bright light on imaging and monitoring biological phenomena within live cells. Its ability to visualize enzyme activities, track metabolic processes, and observe cellular events in real-time is unmatched thanks to its high fluorescence quantum yield, making it a standout in biological imaging.

Enzyme Activity Assays: At the forefront of measuring cytochrome P450 enzyme activities, this compound plays a pivotal role. As a substrate for specific CYP450 enzymes, 7-Ethoxy-4-trifluoromethylcoumarin undergoes metabolism, yielding a fluorescent product that can be quantitatively measured. This method is indispensable for assessing drug metabolism, elucidating the impact of pharmaceuticals on enzyme functions, and shedding light on critical aspects of drug interactions.

Drug Discovery: In the dynamic landscape of drug discovery, 7-Ethoxy-4-trifluoromethylcoumarin emerges as a valuable tool in high-throughput screening assays. Pharmaceutical companies leverage its unique properties to swiftly screen extensive compound libraries for potential drug candidates capable of modulating enzyme activities. Its fluorescence characteristics enable rapid and sensitive detection, positioning it as an indispensable asset in the drug development pipeline, accelerating the quest for innovative therapeutics.

Toxicology Studies: Steering into the realm of toxicological assessments, 7-Ethoxy-4-trifluoromethylcoumarin offers crucial insights into the effects of xenobiotics on liver enzyme functions. Researchers delve into how various compounds impact metabolic pathways involving CYP450 enzymes, key for assessing the toxicological profiles of new chemicals and drugs. These studies are paramount in ensuring human safety, forming the backbone of rigorous evaluations of chemical compounds for potential risks and benefits.