4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside sodium salt | 460085-45-4

Catalog Number	A18-0105
Category	Fluorescent Enzyme Substrates
Molecular Formula	C16H18NNaO10S
Molecular Weight	439.37

Catalog Number	Size	Price	Quantity
A18-0105	--	$--

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Product Introduction

4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate for heparin sulphamidase. 4-MU-α-GlcNS is cleaved by heparin sulphamidase to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent moiety 4-MU. 4-MU-α-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.

Chemical Information
Related CAS	180088-52-2 (free acid)
Synonyms	4-MU-α-GlcNS sodium salt; 2H-1-Benzopyran-2-one, 7-[[2-deoxy-2-(sulfoamino)-α-D-glucopyranosyl]oxy]-4-methyl-, sodium salt (1:1); 7-[[2-deoxy-2-(sulfoamino)-α-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one monosodium salt
Purity	≥98%
IUPAC Name	sodium;N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]sulfamate
Canonical SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)OC3C(C(C(C(O3)CO)O)O)NS(=O)(=O)[O-].[Na+]
InChI	InChI=1S/C16H19NO10S.Na/c1-7-4-12(19)26-10-5-8(2-3-9(7)10)25-16-13(17-28(22,23)24)15(21)14(20)11(6-18)27-16;/h2-5,11,13-18,20-21H,6H2,1H3,(H,22,23,24);/q;+1/p-1/t11-,13-,14-,15-,16+;/m1./s1
InChI Key	LMECUNAMBHBGFU-MYDYNYEJSA-M
Appearance	White Solid
Melting Point	224-229°C (dec.)