5-Carboxytetramethylrhodamine succinimidyl ester | 150810-68-7

Catalog Number	A19-0011
Category	TAMRA Dyes
Molecular Formula	C29H25N3O7
Molecular Weight	527.53

Catalog Number	Size	Price	Quantity
A19-0011	250 mg	$729
A19-0011	--	--

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Product Introduction

5-Carboxytetramethylrhodamine succinimidyl ester is an amine-reactive, orange-fluorescent dye used for labeling DNA and RNA. It also has been used to create bioconjugates with peptides, proteins and enzymes.

Chemical Information
Product Specification

Synonyms	5-TAMRA SE; 5-TAMRA N-succinimidyl ester; 5-Carboxy-tetramethylrhodamine N-succinimidyl ester
IUPAC Name	2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-(2,5-dioxopyrrolidin-1-yl)oxycarbonylbenzoate
Canonical SMILES	CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=C(C=C(C=C4)C(=O)ON5C(=O)CCC5=O)C(=O)[O-]
InChI	InChI=1S/C29H25N3O7/c1-30(2)17-6-9-20-23(14-17)38-24-15-18(31(3)4)7-10-21(24)27(20)19-8-5-16(13-22(19)28(35)36)29(37)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3
InChI Key	VWFRSNKRTNUMET-UHFFFAOYSA-N
Appearance	Solid Powder

Excitation	546 nm
Emission	580 nm

Computed Properties
XLogP3	2.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	527.16925015 g/mol
Monoisotopic Mass	527.16925015 g/mol
Topological Polar Surface Area	119Å²
Heavy Atom Count	39
Formal Charge	0
Complexity	1140
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Literatures

PMID	Publication Date	Title	Journal
23047524	2012-11-21	A DNA based five-state switch with programmed reversibility	Chemical communications (Cambridge, England)
22364288	2012-07-01	Probing the interaction between fluorophores and DNA nucleotides by fluorescence correlation spectroscopy and fluorescence quenching	Photochemistry and photobiology
22740458	2012-07-01	A comparative study of LED-induced fluorescence and laser-induced fluorescence in SDS-CGE: application to the analysis of antibodies	Electrophoresis
22542927	2012-06-01	Monitoring of proteolytic enzyme activity using phase transition-based peptide arrays	Biosensors & bioelectronics
22560162	2012-06-01	Oligonucleotide-based fluorogenic sensor for simultaneous detection of heavy metal ions	Biosensors & bioelectronics

Patents

Publication Number	Title	Priority Date
WO-2022182415-A1	Himastatin derivatives, and processes of preparation thereof, and uses thereof	2021-02-24
CN-112876540-A	Application of an affinity peptide in the preparation of anti-coronavirus drugs	2021-02-09
CN-112876540-B	Application of an affinity peptide in the preparation of anti-coronavirus drugs	2021-02-09
CN-114686599-A	Quantitative detection method and kit for DNA residue content in host insect cells	2020-12-30
CN-112322715-A	A nucleic acid sequencing method	2020-11-17