Z-LLL-AMC

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Z-LLL-AMC

Z-LLL-AMC | 152015-61-7

Catelog Number A18-0063
Category Fluorescent Enzyme Substrates
Molecular Formula C36H48N4O7
Molecular Weight 648.8
Catalog Number Size Price Quantity
A18-0063 -- $--

Product Introduction

Z-LLL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core. AMC (7-amino-4-methylcoumarin) is released to quantify the chymotrypsin-like activity.

Chemical Information

Synonyms N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide; Z-Leu-Leu-Leu-7-amido-4-Methylcoumarin; Proteasome Substrate I
Purity ≥98%
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(CC(C)C)C(=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC3=CC=CC=C3
InChI InChI=1S/C36H48N4O7/c1-21(2)15-28(37-26-13-14-27-24(7)18-32(41)47-31(27)19-26)34(43)40-35(44)29(16-22(3)4)38-33(42)30(17-23(5)6)39-36(45)46-20-25-11-9-8-10-12-25/h8-14,18-19,21-23,28-30,37H,15-17,20H2,1-7H3,(H,38,42)(H,39,45)(H,40,43,44)/t28-,29-,30-/m0/s1
InChI Key MBZJQSNQQJWUBH-DTXPUJKBSA-N
Appearance Solid Powder

Product Specification

Excitation 340-360 nm
Emission 440-460 nm
Storage Store at -20°C
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