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Tyramine hydrochloride | CAS 60-19-5
| Catalog Number | F10-0133 |
| Category | ATTO Dyes |
| Molecular Formula | C8H11NO·HCl |
| Molecular Weight | 173.64 |
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Product Introduction
Tyramine hydrochloride is a biochemical reagent that features an aromatic amine structure, making it suitable for conjugation in fluorescence labeling applications. It serves as a precursor in the synthesis of various fluorescent dyes and probes, where its reactivity with phenolic groups is leveraged for covalent bonding in enzymatic labeling techniques. In research contexts, tyramine hydrochloride is often utilized in the development of tyramide signal amplification (TSA) assays, enhancing detection sensitivity in fluorescence microscopy and other imaging methodologies.
Chemical Information
Product Specification
Computed Properties
Literatures
Patents
Chemical Information
| Synonyms | 4-(2-Aminoethyl)phenol hydrochloride; 4-Hydroxyphenethylamine hydrochloride |
| Purity | 98.0% |
| IUPAC Name | 4-(2-aminoethyl)phenol;hydrochloride |
| SMILES | C1=CC(=CC=C1CCN)O.Cl |
| InChI | InChI=1S/C8H11NO.ClH/c9-6-5-7-1-3-8(10)4-2-7;/h1-4,10H,5-6,9H2;1H |
| InChIKey | RNISDHSYKZAWOK-UHFFFAOYSA-N |
| Melting Point | 271-274 °C (lit.) |
| MDL Number | MFCD00012901 |
| NACRES | NA.77 |
Product Specification
| Storage | Store at 2-8 °C |
| Signal | Warning |
| GHSHazardStatements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (41.71%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 173.0607417 g/mol |
| Monoisotopic Mass | 173.0607417 g/mol |
| Topological Polar Surface Area | 46.2Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 87.3 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 23129510 | 2013-01-01 | Molecular cloning and pharmacological characterisation of a tyramine receptor from the rice stem borer, Chilo suppressalis (Walker) | Pest management science |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-4105323-A1 | New microbial diamine oxidase derived from yarrowia lipolytica for the degradation of biogenic amines | 2021-06-15 |
| WO-2022263031-A1 | New microbial diamine oxidase derived from yarrowia lipolytica for the degradation of biogenic amines | 2021-06-15 |
| KR-20220166396-A | Fire extinguishing product to prevent fire caused by transformer insulating oil | 2021-06-09 |
| WO-2022170012-A1 | Synthesis of peg-based thiol-norbornene hydrogels with tunable hydroylitic degradation properties | 2021-02-08 |
| WO-2022099195-A1 | Ophthalmic formulation containing a dopaminergic prodrug that may be combined with one or more agents | 2020-11-09 |
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