t-Boc-Aminooxy-PEG2-azide | 252378-68-0

Catelog Number	R14-0153
Category	Azides
Molecular Formula	C11H22N4O5
Molecular Weight	290.32

Catalog Number	Size	Price	Quantity
R14-0153	--	$--

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Product Introduction

t-Boc-Aminooxy-PEG2-azide is a crosslinker containing a t-Boc-aminooxy group and an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Aminooxy PEG Linkers may be useful in bioconjugation experiments.

Chemical Information
Synonyms	tert-butyl (2-(2-(2-azidoethoxy)ethoxy)ethoxy)carbamate; Boc-Aminooxy-PEG2-Azide
Purity	≥95%
IUPAC Name	tert-butyl N-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]carbamate
Canonical SMILES	CC(C)(C)OC(=O)NOCCOCCOCCN=[N+]=[N-]
InChI	InChI=1S/C11H22N4O5/c1-11(2,3)20-10(16)14-19-9-8-18-7-6-17-5-4-13-15-12/h4-9H2,1-3H3,(H,14,16)
InChI Key	LBQVKQFGGWKBAN-UHFFFAOYSA-N
Solubility	Soluble in DMSO
Appearance	Pale Yellow Oily Matter

Product Specification
Storage	Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

Computed Properties
XLogP3	1.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	12
Exact Mass	290.15901982 g/mol
Monoisotopic Mass	290.15901982 g/mol
Topological Polar Surface Area	80.4Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	312
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Patents

Publication Number	Title	Priority Date
US-2019151465-A1	Antibody-drug conjugates comprising branched linkers and methods related thereto	2015-11-25
US-2020297865-A1	Conjugates comprising self-immolative groups and methods related thereto	2015-11-25
US-11167040-B2	Conjugates comprising peptide groups and methods related thereto	2015-11-25
US-11173214-B2	Antibody-drug conjugates comprising branched linkers and methods related thereto	2015-11-25
US-2022218840-A1	Antibody-drug conjugates comprising branched linkers and methods related thereto	2015-11-25