Azido-PEG6-NHS ester | 2055014-64-5

Azido-PEG6-NHS ester, a versatile reagent in bioconjugation and bioorthogonal chemistry, finds diverse applications. Here are four key uses showcased with high perplexity and burstiness:

Protein Labeling: Employing azido-PEG6-NHS ester in protein labeling involves the specific attachment of the azido group to lysine residues through amine-reactive NHS ester chemistry. Subsequently, these labeled proteins can undergo further conjugation with alkyne-functionalized molecules via click chemistry, facilitating a myriad of bioanalytical applications.

Drug Delivery: Azido-PEG6-NHS ester plays a pivotal role in crafting targeted drug delivery systems that enhance therapeutic efficacy and reduce off-target effects. By conjugating therapeutic molecules to this reagent and linking them with targeting moieties like antibodies or ligands, researchers refine the precision of drug delivery.

Biomaterials: Functionalizing biomaterials, such as hydrogels and nanoparticles, with azido groups using Azido-PEG6-NHS ester sets the stage for integrating various bioactive compounds through click chemistry. This integration enhances biocompatibility and functionality, particularly in the intricate realm of tissue engineering scaffolds and diagnostic devices, laying the groundwork for cutting-edge developments in regenerative medicine.

Imaging Probes: In the realm of molecular and cellular imaging, the synthesis of imaging probes using azido-PEG6-NHS ester opens new vistas for researchers. By attaching fluorescent dyes or radioactive isotopes to azido-PEG6-NHS ester-labeled biomolecules, researchers can unveil the dynamic tapestry of biological processes in real time, unlocking crucial insights into health and disease mechanisms in a vibrant display of scientific discovery.