Azido-C2-SS-PEG2-C2-acid | CAS 2144777-72-8

Name: Azido-C2-SS-PEG2-C2-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R14-0024
Category	Azides
Molecular Formula	C9H17N3O4S2
Molecular Weight	295.38

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Product Introduction

Chemical Information
Product Specification
Application

Synonyms	Azido-SS-PEG2-acid; 3-(2-(2-((2-azidoethyl)disulfanyl)ethoxy)ethoxy)propanoic acid
Purity	>98.0%
Shelf Life	≥ 2 years
IUPAC Name
Canonical SMILES	C(COCCOCCSSCCN=[N+]=[N-])C(=O)O
InChI	InChI=1S/C9H17N3O4S2/c10-12-11-2-7-17-18-8-6-16-5-4-15-3-1-9(13)14/h1-8H2,(H,13,14)
InChIKey	UGKCXCCDJZIEBX-UHFFFAOYSA-N
Solubility	10 mm in DMSO
Appearance	Solid

Storage

Store at -20 °C, keep in dry and avoid sunlight.

Azido-C2-SS-PEG2-C2-acid, a versatile bifunctional linker, plays a pivotal role in bioconjugation and drug development. Here are four key applications of Azido-C2-SS-PEG2-C2-acid:

Antibody-Drug Conjugates (ADCs): Harnessing the power of Azido-C2-SS-PEG2-C2-acid, researchers delve into the realm of targeted cancer therapy through the synthesis of antibody-drug conjugates. By intricately linking cytotoxic drugs to specific antibodies, this approach ensures the precise delivery of therapeutic payloads to cancer cells while minimizing harm to healthy tissues. The synergy between antibodies and drugs enhances the efficacy and safety profile of chemotherapeutic agents.

Protein Labeling: In the intricate world of molecular biology and proteomics, Azido-C2-SS-PEG2-C2-acid takes center stage for site-specific protein labeling. The azido group facilitates click chemistry conjugation, while the PEG spacer adds a dimension of flexibility and mitigates steric hindrance. This versatile tool enables researchers to explore protein interactions, localization, and function through a myriad of labeling strategies.

Drug Delivery Systems: Pioneering the realm of advanced drug delivery systems, Azido-C2-SS-PEG2-C2-acid offers a gateway to controlled release and targeted delivery of therapeutic agents. By coupling these agents with biodegradable polymers, researchers unlock the potential for tailored treatment regimens with enhanced therapeutic outcomes and reduced side effects. This approach holds promise for addressing a spectrum of diseases, from cancer to inflammatory disorders, with precision and efficacy.

Bioorthogonal Chemistry: Delving into the realm of chemical biology, Azido-C2-SS-PEG2-C2-acid emerges as a linchpin for bioorthogonal chemical reactions within living cells. These reactions unfold seamlessly without disrupting native biochemical processes, offering a window into the intricate tapestry of biological systems. This invaluable tool not only aids in unraveling the complexities of living organisms but also lays the groundwork for innovative diagnostic and therapeutic applications, driving forward the frontiers of biomedical research.