Azido-PEG8-amine | CAS 857891-82-8

Name: Azido-PEG8-amine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R14-0263
Category	Azides
Molecular Formula	C18H38N4O8
Molecular Weight	438.52

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Product Introduction

Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Chemical Information
Product Specification
Computed Properties
Patents

Synonyms	O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol; N3-PEG8-CH2CH2NH2; Azido-PEG8-NH2; N3-PEG8-NH2; 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine
Purity	≥90%
IUPAC Name	2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES	C(COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N
InChI	InChI=1S/C18H38N4O8/c19-1-3-23-5-7-25-9-11-27-13-15-29-17-18-30-16-14-28-12-10-26-8-6-24-4-2-21-22-20/h1-19H2
InChIKey	ZSFGTBJYBWJOLZ-UHFFFAOYSA-N
Appearance	Colorless or Light Yellowish Liquid
LogP	0.54126

Storage	Store at 2-8°C
Signal	Warning
GHSHazardStatements	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

XLogP3	-1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	26
Exact Mass	438.26896418 g/mol
Monoisotopic Mass	438.26896418 g/mol
Topological Polar Surface Area	114Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	376
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Publication Number	Title	Priority Date
WO-2022219409-A2	Compositions containing nucleic acid nanoparticles and processes related to alteration of their physicochemical characteristics	2021-04-15
US-2022072141-A1	Protein-drug conjugates comprising camptothecin analogs and methods of use thereof	2020-07-13
US-2021330810-A1	Compositions containing nucleic acid nanoparticles with modular functionality	2020-04-27
US-11357865-B2	Compositions containing nucleic acid nanoparticles with modular functionality	2020-04-27
US-2022370635-A1	Compositions containing nucleic acid nanoparticles with modular functionality	2020-04-27