Azido-PEG7-amine | 1333154-77-0

Name: Azido-PEG7-amine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	Size	Price	Quantity
R14-0264	--	$--

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Product Introduction

Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Synonyms	Amino-PEG7-azide; 23-azido-3,6,9,12,15,18,21-heptaoxatricosan-1-amine; Azido-PEG7-NH2; N3-PEG7-CH2CH2NH2; N3-PEG7-NH2
Purity	≥95%
IUPAC Name	2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES	C(COCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N
InChI	InChI=1S/C16H34N4O7/c17-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-19-20-18/h1-17H2
InChI Key	VZKXLNRXAFTBOW-UHFFFAOYSA-N
Solubility	Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance	Light Yellow to Light Beige Oily Matter
LogP	0.52466

Storage	Store at 2-8°C under inert atmosphere
Signal	Warning
GHS Hazard Statements	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Computed Properties
XLogP3	-0.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	23
Exact Mass	394.24274944 g/mol
Monoisotopic Mass	394.24274944 g/mol
Topological Polar Surface Area	105Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	334
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Publication Number	Title	Priority Date
WO-2022150721-A1	Bifunctional folate receptor binding compounds	2021-01-08
WO-2021018018-A1	Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inidbitors with e3 ligase ligand and methods of use	2019-07-26
US-2021322331-A1	Nanocapsules for the delivery of cell modulating agents	2018-12-23
CN-113544270-A	Nanocapsules for delivery of cell modulators	2018-12-23
JP-2022514956-A	Nanocapsules for delivery of cell regulators	2018-12-23