Azido-PEG6-t-butyl ester | CAS 406213-76-1

Name: Azido-PEG6-t-butyl ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Product Introduction

Azido-PEG6-C2-Boc is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG6-C2-Boc can be used in the synthesis of a series of PROTACs.

Synonyms	N3-PEG6-CH2CH2COOtBu; 2-Methyl-2-propanyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate; N3-PEG6-tBu; Azido-PEG6-C2-Boc; tert-butyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate; Azido-PEG6-Boc; 3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-, 1,1-dimethylethyl ester; 21-Azido-4,7,10,13,16,19-hexaoxaheneicosanoic acid 1,1-dimethylethyl ester
Purity	>97%
IUPAC Name	tert-butyl 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES	CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
InChI	InChI=1S/C19H37N3O8/c1-19(2,3)30-18(23)4-6-24-8-10-26-12-14-28-16-17-29-15-13-27-11-9-25-7-5-21-22-20/h4-17H2,1-3H3
InChIKey	HRNUWAOLFSWRDG-UHFFFAOYSA-N
Solubility	Soluble in DMSO
Appearance	Colorless Liquid

Storage

Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

XLogP3	1.1
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	23
Exact Mass	435.25806515 g/mol
Monoisotopic Mass	435.25806515 g/mol
Topological Polar Surface Area	96Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	454
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Publication Number	Title	Priority Date
US-2018161446-A1	Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof	2015-06-09
EP-2917195-B9	Spliceostatin analogs	2012-11-05
US-2014134193-A1	Spliceostatin analogs and methods for their preparation	2012-11-05
US-2016022626-A1	Spliceostatin analogs and methods for their preparation	2012-11-05
US-2017014523-A1	Spliceostatin analogs and methos for their preparation	2012-11-05