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Azido-PEG6-alcohol | 86770-69-6
| Catalog Number | R14-0216 |
| Category | Azides |
| Molecular Formula | C12H25N3O6 |
| Molecular Weight | 307.34 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R14-0216 | -- | $-- |
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Product Introduction
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Chemical Information |
|
|---|---|
| Synonyms | N3-PEG6-OH; 17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol |
| Purity | >98.0% |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| IUPAC Name | 2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| Canonical SMILES | C(COCCOCCOCCOCCOCCO)N=[N+]=[N-] |
| InChI | InChI=1S/C12H25N3O6/c13-15-14-1-3-17-5-7-19-9-11-21-12-10-20-8-6-18-4-2-16/h16H,1-12H2 |
| InChI Key | DPRULTZUGLDCPZ-UHFFFAOYSA-N |
| Solubility | 10 mm in DMSO |
| Appearance | Solid |
- Product Specification
| Storage | Store at -20 °C, keep in dry and avoid sunlight. |
Computed Properties | |
|---|---|
| XLogP3 | -0.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 17 |
| Exact Mass | 307.17433553 g/mol |
| Monoisotopic Mass | 307.17433553 g/mol |
| Topological Polar Surface Area | 80.7Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 251 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2020139807-A2 | Nanocapsules for the delivery of cell modulating agents | 2018-12-23 |
| AU-2019414331-A1 | Nanocapsules for the delivery of cell modulating agents | 2018-12-23 |
| EP-3898978-A2 | Nanocapsules for the delivery of cell modulating agents | 2018-12-23 |
| US-2021322331-A1 | Nanocapsules for the delivery of cell modulating agents | 2018-12-23 |
| CN-113544270-A | Nanocapsules for delivery of cell modulators | 2018-12-23 |
Applications of Fluorescent Probes & Dyes
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