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Azido-PEG4-hydrazide | 2170240-96-5
| Catalog Number | R14-0251 |
| Category | Azides |
| Molecular Formula | C₁₁H₂₃N₅O₅ |
| Molecular Weight | 305.33 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R14-0251 | -- | $-- |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Azido-PEG4-hydrazide is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG4-hydrazide can be used in the synthesis of a series of PROTACs.
- Chemical Information
- Product Specification
| Synonyms | Azido-PEG4-hydrazide HCl Salt;N3-PEG4-Hydrazide |
| Purity | >95% |
| IUPAC Name | 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanehydrazide |
| Canonical SMILES | C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)NN |
| InChI | InChI=1S/C11H23N5O5/c12-15-11(17)1-3-18-5-7-20-9-10-21-8-6-19-4-2-14-16-13/h1-10,12H2,(H,15,17) |
| InChI Key | BUAWGAVOHIVJRC-UHFFFAOYSA-N |
| Solubility | In DMSO: 100 mg/mL (327.51 mM; Need ultrasonic) |
| Storage | -20°C, protect from light; In solvent, -80°C, 6 months; -20°C, 1 month (protect from light) |
Computed Properties | |
|---|---|
| XLogP3 | -1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 15 |
| Exact Mass | 305.16991885 g/mol |
| Monoisotopic Mass | 305.16991885 g/mol |
| Topological Polar Surface Area | 106Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 299 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022265493-A1 | Conjugate of saponin, oligonucleotide and galnac | 2021-06-18 |
| WO-2020126064-A1 | Saponin conjugated to epitope-binding proteins | 2018-12-21 |
| WO-2020126604-A1 | Saponin conjugates | 2018-12-21 |
| WO-2020126620-A2 | Improved antibody-oligonucleotide conjugate | 2018-12-21 |
| WO-2020126626-A1 | Biologically active cluster of molecules | 2018-12-21 |
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