Azido-PEG1-acid

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Azido-PEG1-acid

Azido-PEG1-acid | 1393330-34-1

Catalog Number R14-0290
Category Azides
Molecular Formula C5H9N3O3
Molecular Weight 159.14
Catalog Number Size Price Quantity
R14-0290 -- $--

Product Introduction

Azido-PEG1-C2-acid is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG1-C2-acid can be used in the synthesis of a series of PROTACs.

Chemical Information

Related CAS 1167575-20-3 (polymer)
Synonyms N3-PEG1-COOH; Azido-PEG1-C2-acid; Propanoic acid, 3-(2-azidoethoxy)-
Purity >95%
IUPAC Name 3-(2-azidoethoxy)propanoic acid
Canonical SMILES C(COCCN=[N+]=[N-])C(=O)O
InChI InChI=1S/C5H9N3O3/c6-8-7-2-4-11-3-1-5(9)10/h1-4H2,(H,9,10)
InChI Key JKOVLUVEHHGAEW-UHFFFAOYSA-N
Solubility Water, DMSO, DMF, DCM
Appearance Transparent Liquid
  • Product Specification
Storage Store at 2-8°C

Computed Properties

XLogP3 0.5
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 6
Exact Mass 159.06439116 g/mol
Monoisotopic Mass 159.06439116 g/mol
Topological Polar Surface Area 60.9Ų
Heavy Atom Count 11
Formal Charge 0
Complexity 164
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
US-2012225089-A1 Novel conjugates, preparation thereof, and therapeutic use thereof 2009-06-29
US-8952147-B2 Conjugates, preparation thereof, and therapeutic use thereof 2009-06-29
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