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AmdU (5-azidomethyl-2'-deoxyuridine)
| Catalog Number | R14-0001 |
| Category | Azides |
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.24 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU.,Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.
Chemical Information
Product Specification
| Purity | NMR 1H, HPLC-MS (95%) |
| Solubility | Good in water, alcohols, DMSO, DMF |
| Appearance | White / Off white solid |
| Storage | Storage: 24 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
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