AmdU (5-azidomethyl-2'-deoxyuridine)

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AmdU (5-azidomethyl-2'-deoxyuridine)

AmdU (5-azidomethyl-2'-deoxyuridine)

Catalog Number R14-0001
Category Azides
Molecular Formula C10H13N5O5
Molecular Weight 283.24
Catalog Number Size Price Quantity
R14-0001 -- $--

Product Introduction

Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU.,Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.

Chemical Information

Purity NMR 1H, HPLC-MS (95%)
Solubility Good in water, alcohols, DMSO, DMF
Appearance White / Off white solid
  • Product Specification
Storage Storage: 24 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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