
8-Azido-3,6-dioxaoctanoic acid tert-butyl ester | CAS 251564-45-1
| Catalog Number | R14-0225 |
| Category | Azides |
| Molecular Formula | C10H19N3O4 |
| Molecular Weight | 245.28 |
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Product Introduction
8-Azido-3,6-dioxaoctanoic acid tert-butyl ester is a versatile azido-functionalized PEG derivative presented as a stable, crystalline solid. The molecule's azide group enables efficient participation in click chemistry reactions, facilitating site-specific conjugation and bioconjugate synthesis. Inclusion of a tert-butyl ester protects the carboxyl function, allowing selective deprotection for downstream modifications. Favored in peptide coupling, polymer modification, and drug linker research, it serves as a valuable tool in chemical biology and bioorthogonal labeling strategies.
Chemical Information
Product Specification
| Synonyms | Azido-PEG2-CH2CO2tBu; N3-AEEA-OtBu; tert-butyl 8-azido-3,6-dioxaoctanoate; Azido-PEG2-C1-Boc; N3-PEG2-CH2COOtBu; Azido-PEG2-CH2CO2-t-Bu; tert-butyl 2-[2-(2-azidoethoxy)ethoxy]acetate; N3 AEEA OtBu |
| Purity | ≥ 95% (GC) |
| IUPAC Name | tert-butyl 2-[2-(2-azidoethoxy)ethoxy]acetate |
| Canonical SMILES | CC(C)(C)OC(=O)COCCOCCN=[N+]=[N-] |
| InChI | InChI=1S/C10H19N3O4/c1-10(2,3)17-9(14)8-16-7-6-15-5-4-12-13-11/h4-8H2,1-3H3 |
| InChIKey | VVSLXAHQRLHPKS-UHFFFAOYSA-N |
| Solubility | DMSO, DCM, DMF |
| Appearance | Colorless oil |
| Storage | Store at 2-8 °C |
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