6-JOE Azide, CHC protected

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6-JOE Azide, CHC protected

6-JOE Azide, CHC protected

Catalog Number F12-0006
Category Azides
Molecular Formula C40H40Cl2N4O10
Molecular Weight 807.68
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Product Introduction

6-JOE Azide, CHC protected is a fluorescent labeling reagent featuring a 6-carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein (6-JOE) fluorophore with cyclohexylcarbonyl (CHC) protecting groups on the phenolic hydroxyl groups, conjugated to an azide functional group. The azide moiety enables bioorthogonal click chemistry reactions, while the CHC protection enhances stability during synthesis and handling. It is used in oligonucleotide modification, surface functionalization, and bioconjugation applications.

  • Chemical Information

Chemical Information

Synonyms JOE azide, 6-isomer, CHC protected; 6-((3-Azidopropyl)carbamoyl)-4',5'-dichloro-2',7'-dimethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl dicyclohexanecarboxylate
SMILES [N-]=[N+]=NCCCNC(C(C=C1C23C(C=C4OC)=C(OC(C(Cl)=C5OC(C6CCCCC6)=O)=C2C=C5OC)C(Cl)=C4OC(C7CCCCC7)=O)=CC=C1C(O3)=O)=O
InChI InChI=1S/C40H40Cl2N4O10/c1-51-28-19-26-32(30(41)34(28)54-37(48)21-10-5-3-6-11-21)53-33-27(20-29(52-2)35(31(33)42)55-38(49)22-12-7-4-8-13-22)40(26)25-18-23(14-15-24(25)39(50)56-40)36(47)44-16-9-17-45-46-43/h14-15,18-22H,3-13,16-17H2,1-2H3,(H,44,47)
InChIKey WUHHVXILENJOOE-UHFFFAOYSA-N

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