6-JOE Azide

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6-JOE Azide

6-JOE Azide

Catalog Number F12-0005
Category Azides
Molecular Formula C26H20Cl2N4O8
Molecular Weight 587.37
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Product Introduction

6-JOE Azide is a fluorescent labeling reagent featuring a 6-carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein (6-JOE) fluorophore conjugated to an azide functional group. The azide moiety enables bioorthogonal click chemistry reactions, particularly copper-catalyzed or strain-promoted azide-alkyne cycloaddition, allowing selective and efficient labeling of biomolecules. It is used in oligonucleotide modification, surface functionalization, and bioconjugation applications.

  • Chemical Information

Chemical Information

Synonyms JOE azide, 6-isomer; N-(3-Azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxamide; Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxamide, N-(3-azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-; N-(3-Azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamide
IUPAC Name N-(3-azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-6-carboxamide
SMILES [N-]=[N+]=NCCCNC(C(C=C1C23C(C=C4OC)=C(OC(C(Cl)=C5O)=C2C=C5OC)C(Cl)=C4O)=CC=C1C(O3)=O)=O
InChI InChI=1S/C26H20Cl2N4O8/c1-37-16-9-14-22(18(27)20(16)33)39-23-15(10-17(38-2)21(34)19(23)28)26(14)13-8-11(4-5-12(13)25(36)40-26)24(35)30-6-3-7-31-32-29/h4-5,8-10,33-34H,3,6-7H2,1-2H3,(H,30,35)
InChIKey HRUDZJYFTFXSBO-UHFFFAOYSA-N

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