5-JOE Azide | CAS 1422178-11-7

Name: 5-JOE Azide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	F12-0003
Category	Azides
Molecular Formula	C26H20Cl2N4O8
Molecular Weight	587.37

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Product Introduction

5-JOE Azide is a fluorescent labeling reagent featuring a 5-carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein (5-JOE) fluorophore conjugated to an azide functional group. The azide moiety enables bioorthogonal click chemistry reactions, particularly copper-catalyzed or strain-promoted azide-alkyne cycloaddition, allowing selective and efficient labeling of biomolecules. It is used in oligonucleotide modification, surface functionalization, and bioconjugation applications.

Chemical Information
Product Specification

Chemical Information

Synonyms	JOE azide, 5-isomer; N-(3-Azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxamide; Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxamide, N-(3-azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-; N-(3-Azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamide
IUPAC Name	N-(3-azidopropyl)-4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxamide
SMILES	COC1=C(C(=C2C(=C1)C3(C4=C(C=C(C=C4)C(=O)NCCCN=[N+]=[N-])C(=O)O3)C5=CC(=C(C(=C5O2)Cl)O)OC)Cl)O
InChI	InChI=1S/C26H20Cl2N4O8/c1-37-16-9-14-22(18(27)20(16)33)39-23-15(10-17(38-2)21(34)19(23)28)26(14)13-5-4-11(8-12(13)25(36)40-26)24(35)30-6-3-7-31-32-29/h4-5,8-10,33-34H,3,6-7H2,1-2H3,(H,30,35)
InChIKey	HEOCCOHXKKBACD-UHFFFAOYSA-N
Solubility	Soluble in DMF, DMSO
Appearance	Red solid