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5-Carboxynaphthofluorescein diacetate | CAS 164256-07-9
| Catalog Number | A18-0074 |
| Category | Fluorescent Enzyme Substrates |
| Molecular Formula | C33H20O9 |
| Molecular Weight | 560.52 |
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Product Introduction
5-Carboxynaphthofluorescein diacetate is a cell-permeable fluorogenic probe that features a naphthofluorescein chromophore, which is known for its extended conjugated aromatic system and distinct spectral properties. Upon intracellular ester hydrolysis, it releases the fluorescent 5-carboxynaphthofluorescein, which exhibits environment-sensitive fluorescence, making it suitable for imaging applications in live cell assays. This compound is often utilized in the study of intracellular pH dynamics due to its responsive fluorescence behavior under varying pH conditions, thereby supporting research in cellular biology and related fields.
Chemical Information
Chemical Information
| Related CAS | 163831-68-3 (5(6)-Carboxynaphthofluorescein diacetate) |
| Synonyms | 5(6)-Carboxynaphthofluorescein diacetate;Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-5'-carboxylic acid, 3,11-bis(acetyloxy)-3'-oxo-; 3,11-Bis(acetyloxy)-3'-oxospiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-5'-carboxylic acid; 3,11-Diacetoxy-3'-oxo-3'H-spiro[dibenzo[c,h]xanthene-7,1'-isobenzofuran]-5'-carboxylic acid; CNFDA |
| Purity | ≥95% |
| IUPAC Name | 7',19'-diacetyloxy-3-oxospiro[2-benzofuran-1,13'-2-oxapentacyclo[12.8.0.03,12.04,9.017,22]docosa-1(14),3(12),4(9),5,7,10,15,17(22),18,20-decaene]-5-carboxylic acid |
| SMILES | CC(=O)OC1=CC2=C(C=C1)C3=C(C=C2)C4(C5=C(C=C(C=C5)C(=O)O)C(=O)O4)C6=C(O3)C7=C(C=C6)C=C(C=C7)OC(=O)C |
| InChI | InChI=1S/C33H20O9/c1-16(34)39-21-6-8-23-18(13-21)3-11-27-29(23)41-30-24-9-7-22(40-17(2)35)14-19(24)4-12-28(30)33(27)26-10-5-20(31(36)37)15-25(26)32(38)42-33/h3-15H,1-2H3,(H,36,37) |
| InChIKey | UEAWZAKAKAFAES-UHFFFAOYSA-N |
| Density | 1.56±0.1 g/cm3 |
| Boiling Point | 828.4±65.0°C at 760 mmHg |
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