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Mca-DEVDAPK(Dnp)-OH | 189696-20-6
| Catalog Number | A18-0042 |
| Category | Fluorescent Enzyme Substrates |
| Molecular Formula | C50H62N10O22 |
| Molecular Weight | 1155.1 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A18-0042 | -- | $-- |
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Product Introduction
Mca-DEVDAPK(Dnp)-OH is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify caspase-3 activity.
Chemical Information |
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| Synonyms | Caspase-3 Fluorogenic Substrate III; CPP32 Fluorogenic Substrate III; 7-Methoxycoumarin-4-acetyl-DEVDAPK(Dnp)-OH; N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine |
| Purity | ≥95% |
| Canonical SMILES | CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(CCCCNC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-])C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CC3=CC(=O)OC4=C3C=CC(=C4)OC |
| InChI | InChI=1S/C50H62N10O22/c1-24(2)43(57-44(69)31(14-15-39(62)63)54-46(71)33(22-40(64)65)53-38(61)18-26-19-42(68)82-37-21-28(81-4)11-12-29(26)37)48(73)56-34(23-41(66)67)45(70)52-25(3)49(74)58-17-7-9-35(58)47(72)55-32(50(75)76)8-5-6-16-51-30-13-10-27(59(77)78)20-36(30)60(79)80/h10-13,19-21,24-25,31-35,43,51H,5-9,14-18,22-23H2,1-4H3,(H,52,70)(H,53,61)(H,54,71)(H,55,72)(H,56,73)(H,57,69)(H,62,63)(H,64,65)(H,66,67)(H,75,76)/t25-,31-,32-,33-,34-,35-,43-/m0/s1 |
| InChI Key | YOUVSUDOGAVRQX-AEAFXXELSA-N |
- Product Specification
| Storage | Store at -20°C |
Applications of Fluorescent Probes & Dyes
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