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Dihydrotetramethylrosamine | CAS 105284-17-1
| Catalog Number | A18-0067 |
| Category | Fluorescent Enzyme Substrates |
| Molecular Formula | C23H24N2O |
| Molecular Weight | 344.46 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Dihydrotetramethylrosamine is a mitochondrial ROS indicator offering strong red fluorescence upon oxidation. It’s used for tracking mitochondrial oxidative stress in live cells.
Chemical Information
Computed Properties
Patents
| Synonyms | H2TMRos; 3-N,3-N,6-N,6-N-tetramethyl-9-phenyl-9H-xanthene-3,6-diamine |
| IUPAC Name | 3-N,3-N,6-N,6-N-tetramethyl-9-phenyl-9H-xanthene-3,6-diamine |
| Canonical SMILES | CN(C)C1=CC2=C(C=C1)C(C3=C(O2)C=C(C=C3)N(C)C)C4=CC=CC=C4 |
| InChI | InChI=1S/C23H24N2O/c1-24(2)17-10-12-19-21(14-17)26-22-15-18(25(3)4)11-13-20(22)23(19)16-8-6-5-7-9-16/h5-15,23H,1-4H3 |
| InChIKey | PALQHVVMLBWIDW-UHFFFAOYSA-N |
| XLogP3 | 5.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 344.188863393 g/mol |
| Monoisotopic Mass | 344.188863393 g/mol |
| Topological Polar Surface Area | 15.7Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 427 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2021168290-A1 | Multilamellar rna nanoparticles and methods of sensitizing tumors to treatment with immune checkpoint inhibitors | 2020-02-19 |
| WO-2020119766-A1 | Nanoparticles based method for screening enzyme or microorganism | 2018-12-14 |
| EP-3893849-A1 | Nanoparticles based method for screening enzyme or microorganism | 2018-12-14 |
| US-2022056387-A1 | Nanoparticles based method for screening enzyme or microorganism | 2018-12-14 |
| US-2020080117-A1 | REAGENTS AND METHODS FOR THE EXPRESSION OF AN ACTIVE NifB PROTEIN AND USES THEREOF | 2018-09-12 |
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