Dibenzylfluorescein | 97744-44-0

Catalog Number	A18-0002
Category	Fluorescent Enzyme Substrates
Molecular Formula	C34H24O5
Molecular Weight	512.6

Catalog Number	Size	Price	Quantity
A18-0002	--	$--

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Product Introduction

Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein produces fluorescein benzyl ether when dealkylated by these CYP isoforms, which is further hydrolyzed to fluorescein by the addition of base (typically 2 M NaOH). It is used for detecting changes in catalytic activity by medication or the onset of disease.

Chemical Information
Synonyms	2-[3-oxo-6-(phenylmethoxy)-3H-xanthen-9-yl]-benzoic acid, phenylmethyl ester; DBF; O-Benzylfluorescein benzyl ester; Benzyl 2-[6-(benzyloxy)-3-oxo-3H-xanthen-9-yl]benzoate
Purity	≥98%
Canonical SMILES	C1=CC=C(C=C1)COC2=CC3=C(C=C2)C(=C4C=CC(=O)C=C4O3)C5=CC=CC=C5C(=O)OCC6=CC=CC=C6
InChI	InChI=1S/C34H24O5/c35-25-15-17-29-31(19-25)39-32-20-26(37-21-23-9-3-1-4-10-23)16-18-30(32)33(29)27-13-7-8-14-28(27)34(36)38-22-24-11-5-2-6-12-24/h1-20H,21-22H2
InChI Key	YZJGKSLPSGPFEV-UHFFFAOYSA-N
Appearance	Orange Solid
Melting Point	>179°C (dec.)