4-Methylumbelliferyl Palmitate

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4-Methylumbelliferyl Palmitate

4-Methylumbelliferyl Palmitate | 17695-48-6

Catelog Number A18-0102
Category Fluorescent Enzyme Substrates
Molecular Formula C26H38O4
Molecular Weight 414.6
Catalog Number Size Price Quantity
A18-0102 -- $--

Product Introduction

4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU.

Chemical Information

Synonyms 4-MUP; 4-MU Palmitate; Palmitoyl 4-Methylumbelliferone; hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
Purity ≥98%
IUPAC Name (4-methyl-2-oxochromen-7-yl) hexadecanoate
Canonical SMILES CCCCCCCCCCCCCCCC(=O)OC1=CC2=C(C=C1)C(=CC(=O)O2)C
InChI InChI=1S/C26H38O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(27)29-22-17-18-23-21(2)19-26(28)30-24(23)20-22/h17-20H,3-16H2,1-2H3
InChI Key QKQVFFACWLFRRX-UHFFFAOYSA-N
Appearance White to Off-white Solid
Melting Point 75-77ºC

Product Specification

Storage Store at -20°C
Signal Warning
GHS Hazard Statements H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

Computed Properties

Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 16
Exact Mass 414.27700969 g/mol
Monoisotopic Mass 414.27700969 g/mol
Topological Polar Surface Area 52.6Ų
Heavy Atom Count 30
Formal Charge 0
Complexity 539
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Literatures

PMIDPublication DateTitleJournal
22483793 2012-08-16 A new method for the measurement of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2 Clinica chimica acta; international journal of clinical chemistry

Patents

Publication NumberTitlePriority Date
WO-2022263950-A1 Biological indicator with adjusted resistance characteristics 2021-06-16
WO-2022164860-A1 Materials and methods for the treatment of lysosomal acid lipase deficiency (lal-d) 2021-01-27
WO-2022034498-A1 Moving-front sterilization monitoring devices 2020-08-12
WO-2021214595-A1 Biological indicator with test microorganisms enveloped by wax composition 2020-04-22
WO-2021186267-A1 Immobilized ph indicator for biological indicator growth indication 2020-03-17
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