N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5 | CAS 2107273-80-1

Name: N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	A17-0172
Category	Cyanine5
Molecular Formula	C₃₇H₄₉ClN₂O₉S₂
Molecular Weight	765.38

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Product Introduction

N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5 is a polyethylene glycol (PEG)-based PROTAC linker. N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5 can be used in the synthesis of a series of PROTACs.

Chemical Information
Product Specification
Application

Purity	98%
IUPAC Name	3-[2-[2-[2-[2-[5-[3-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl]-1,3-benzothiazol-2-ylidene]penta-1,3-dienyl]-1,3-benzothiazol-3-ium-3-yl]ethoxy]ethoxy]ethoxy]propanoic acid;chloride
Canonical SMILES	COCCOCCOCCOCCN1C2=CC=CC=C2SC1=CC=CC=CC3=[N+](C4=CC=CC=C4S3)CCOCCOCCOCCC(=O)O.[Cl-]
InChI	InChI=1S/C37H48N2O9S2.ClH/c1-42-21-22-46-29-30-48-28-25-45-20-17-39-32-10-6-8-12-34(32)50-36(39)14-4-2-3-13-35-38(31-9-5-7-11-33(31)49-35)16-19-44-24-27-47-26-23-43-18-15-37(40)41;/h2-14H,15-30H2,1H3;1H
InChIKey	PEWXFUQTWHPFTH-UHFFFAOYSA-N
Solubility	Water, DMSO, DMF, DCM

Excitation	649
Emission	667
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5, a fluorescent dye widely utilized in diverse bioscience applications, offers a multitude of uses. Here are four key applications showcasing the high degree of perplexity and burstiness:

Fluorescence Imaging: At the forefront of biological research, N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5 serves as a pivotal tool for fluorescence imaging. By labeling biomolecules like proteins and nucleic acids, researchers unveil the intricacies of cellular processes and molecular interactions with unparalleled precision. This real-time visualization under fluorescence microscopy provides insights into dynamic biological phenomena.

Flow Cytometry: Delving into the realm of cell sorting and analysis, this fluorescent dye plays a crucial role in flow cytometry. Conjugated with antibodies or ligands, Cy5 facilitates the identification and quantification of specific cell populations based on fluorescence signals. This application holds significance in fields ranging from immunology to cancer research, enabling detailed exploration of cellular dynamics and functions.

In Vivo Imaging: With its near-infrared fluorescence properties, N-(m-PEG4)-N'-(Acid-PEG3)-benzothiazole Cy5 is ideal for in vivo imaging studies allowing deep tissue penetration. By labeling cells, tissues, or small animals, researchers can track biological processes like tumor growth or drug delivery in living organisms. This non-invasive approach aids in understanding physiological and pathological conditions intricately.

Molecular Probes: Embedded in molecular probes, this dye enhances the detection of specific targets in assays such as ELISA and Western blotting. By coupling Cy5 with probes, researchers achieve sensitive and accurate identification of proteins, nucleic acids, and other biomolecules. This application serves as a cornerstone in diagnostics and research methodologies, enabling precise molecular characterization with finesse.