![{[Name]}](/probes/images/structure-default.jpg?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/75539-51-4.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2107273-48-1.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2107273-36-7.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/1263093-76-0.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/146368-15-2.gif?v=2025011501)
Inquiry Basket
N-PEG3-N'-(propargyl-PEG4)-Cy5 | CAS 2107273-06-1
| Catalog Number | A17-0159 |
| Category | Cyanine5 |
| Molecular Formula | C₄₂H₅₇ClN₂O₇ |
| Molecular Weight | 737.36 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
N-PEG3-N'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based PROTAC linker. N-PEG3-N'-(propargyl-PEG4)-Cy5 can be used in the synthesis of a series of PROTACs.
Chemical Information
Product Specification
Application
| Synonyms | N-(hydroxy-PEG2)-N'-(propargyl-PEG4)-Cy5 |
| Purity | 97% |
| IUPAC Name | 2-[2-[2-[2-[(1E,3E)-5-[3,3-dimethyl-1-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyl]indol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]ethoxy]ethoxy]ethanol;chloride |
| Canonical SMILES | CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCOCCOCCOCCOCC#C)(C)C)CCOCCOCCO)C.[Cl-] |
| InChI | InChI=1S/C42H57N2O7.ClH/c1-6-23-46-27-31-50-33-34-51-32-29-48-25-21-44-38-17-13-11-15-36(38)42(4,5)40(44)19-9-7-8-18-39-41(2,3)35-14-10-12-16-37(35)43(39)20-24-47-28-30-49-26-22-45;/h1,7-19,45H,20-34H2,2-5H3;1H/q+1;/p-1 |
| InChIKey | MXPPWWDNHJQAKX-UHFFFAOYSA-M |
| Solubility | Water, DMSO, DMF, DCM |
| Excitation | 649 |
| Emission | 667 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
One of the primary applications of N-PEG3-N'-(propargyl-PEG4)-Cy5 is in fluorescence imaging. The Cy5 dye is well-known for its strong fluorescence and photostability, making it ideal for in vivo and in vitro imaging. Researchers often utilize this compound in biological studies to visualize cellular processes, track the movement of proteins, and monitor drug delivery systems. Its high quantum yield enables sensitive detection, which is crucial in applications such as cancer research, where tracking tumor progression and response to therapies is essential. This capability to provide real-time imaging insights enhances the understanding of complex biological phenomena.
Another significant application is in the development of targeted drug delivery systems. N-PEG3-N'-(propargyl-PEG4)-Cy5 can be conjugated to therapeutic agents, allowing for the visualization of drug distribution within biological systems. This is particularly valuable in cancer therapy, where targeted delivery minimizes off-target effects and maximizes therapeutic efficacy. By integrating Cy5 with drug molecules, researchers can monitor how effectively drugs reach their intended targets, optimizing formulations and enhancing therapeutic outcomes. This targeted approach holds promise for improving the specificity and effectiveness of treatments.
N-PEG3-N'-(propargyl-PEG4)-Cy5 is also employed in the field of biosensing and diagnostics. The ability of Cy5 to emit fluorescence upon excitation allows it to be incorporated into biosensors that detect biomolecules, such as proteins or nucleic acids. These sensors can provide rapid and sensitive readouts, facilitating early diagnosis of diseases. For instance, in point-of-care testing, this compound can enhance the performance of assays, making it possible to detect low-abundance biomarkers in complex samples. This capability is particularly important in infectious disease diagnostics, where early detection can significantly impact patient outcomes.
Finally, N-PEG3-N'-(propargyl-PEG4)-Cy5 plays a crucial role in materials science, particularly in the development of smart materials and nanotechnology applications. By incorporating Cy5 into polymeric matrices or nanocarriers, researchers can create materials that respond to environmental stimuli, such as changes in pH or temperature. These smart materials can be utilized in drug delivery systems, where the release of therapeutic agents can be controlled by external triggers, providing a significant advantage in therapeutic applications. The versatility of this compound in material formulations opens avenues for innovative solutions across various industries, including biomedicine and materials engineering.
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
